نتایج جستجو برای: drug exposure
تعداد نتایج: 862020 فیلتر نتایج به سال:
health care workers (hcw) are at high risk of occupational exposure from blood-borne pathogens. the most important pathogens that can be transmitted to hcw are hiv with prevalence of 2.24 per 100000, hbv with prevalence of 2.3%, and hcv with prevalence of 0.2% in iran. most of this occupational transmission can be prevented through standard precautions reducing exposure. these precautions, howe...
BACKGROUND Older people carry a high burden of illness for which medications are indicated, along with increased risk of adverse drug reactions. We developed an index to determine drug burden based on pharmacologic principles. We evaluated the relationship of this index to physical and cognitive performance apart from disease indication. METHODS Data from the Health, Aging, and Body Compositi...
The aim of the present investigation was to formulate thermally sintered floating tablets of propranolol HCl, and to study the effect of sintering conditions on drug release, as well as their in vitro buoyancy properties. A hydrophilic polymer, polyethylene oxide, was selected as a sintered polymer to retard the drug release. The formulations were prepared by a direct compression method and wer...
conclusions the high prevalence of hcv infection among this group implies a high rate of transmission and exposure to the risk of serious diseases. it is important that the high prevalence of hcv infection be taken into consideration to control further transmission of this infection. background hepatitis c is an infectious disease caused by blood-borne pathogen, hepatitis c virus (hcv). objecti...
BACKGROUND Identifying predictive biomarkers of drug response is of key importance to improve therapy management and drug selection in cancer therapy. To date, the influence of drug exposure and pharmacogenetic variants on sorafenib-induced toxicity remains poorly documented. The aim of this pharmacokinetic/pharmacodynamic (PK/PD) study was to investigate the relationship between early toxicity...
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