Clinically significant delayed absorption after lithium overdose has been reported previously without adequate explanation. We have studied two patients after they took massive intentional lithium overdoses. The first patient presented shortly after ingesting 74 g of lithium carbonate. Pharmacokinetic analysis with a multicompartmental model of 29 serum lithium concentrations during 300 h (incl...

A smokeable product called Kronic, is legally available, sold under five product names, and marketed in New Zealand as containing natural extracts. Two such products called Pineapple Express and Purple Haze were purchased from shops in Auckland city. They were investigated for the presence of synthetic drugs specifically synthesized for recreational purposes. The synthetic cannabinomimetics ide...

Automated food processing and evaluation is considered a significant research area in computer vision. The development of automated cooking and food serving by robots is envisaged as part of automated food processing and temperature plays a major role in cooking Indian foods. The delicious Indian foods are generally boiled or fried with other ingredients. The boiled grains like Bengal Gram, Bla...

Outcome Number of studies Odds ratio Confidence interval (95% confidence level) Reduction in Needle Sharing 6 3.22 2.17-4.77 Needle and Syringe Programs (NSPs) are interventions that provide drug preparation and injection equipment to injection drug users to decrease equipment sharing, and consequently, HIV transmission risk. Drug equipment may include needles, syringes, and other ancillary mat...

The provision of pure enantiomers is of increasing importance not only for the pharmaceutical industry but also for agro-chemistry and biotechnology. In drug discovery and development, the enantiomers of a chiral drug depict unique chemical and pharmacological behaviors in a chiral environment, such as the human body, in which the stereochemistry of the chiral drugs determines their pharmacokin...

Automated food processing and evaluation is considered a significant research area in computer vision. The development of automated cooking and food serving by robots is envisaged as part of automated food processing and temperature plays a major role in cooking Indian foods. The delicious Indian foods are generally boiled or fried with other ingredients. The boiled grains like Bengal Gram, Bla...

Based on the findings that the pH in malignant tumors can be preferentially decreased by stimulation of their aerobic glycolysis, acid-sensible prodrugs, which are nearly nontoxic at physiological pH, were synthesized. At lower pH, however, these compounds are cleaved with liberation of a cytotoxic species. The prototypic drug compound 2-hexenopyranoside of aldophosphamide was prepared, which r...

A Clinical trial of Indigenous compound drug 'Nishamalaki' was carried out in the CRI (Ayurveda) Hospital, Jaipur on the patient of Madhumeha. For this study, patients were randomly divided into two groups of 25 individuals each and they were termed as group A and B. The individuals of group a were administered Nishamalaki in a dose of one gram twice daily along with diet control, the patients ...

One of the least-developed areas of clinical pharmacology and drug research is the use of medication during pregnancy and lactation. This article is the first in a two-part series designed to familiarize physicians with many aspects of the drugs they commonly prescribe for pregnant and breast-feeding women. Almost every pregnant woman is exposed to some type of medication during pregnancy. Alth...

Background: Cancer patients who receive anthracycline-based chemotherapy regimens often discontinue due to cardiotoxicity. Preventing and reducing anthracycline-induced cardiotoxicity (ACT) is a hot topic in cardio-oncology research. Network pharmacology new discipline that integrates pharmacology, bioinformatics, systems biology. It can be used analyze the mechanism of action drugs body from h...