Using an electronic inhaler timer device (Nebulizer Chronolog), compliance with the prescribed frequency of inhaled prophylactic medication in 14 asthmatic children was measured. Underuse occurred in 55% of study days while overuse occurred in only 2%. Such devices provide an important new tool for investigating inhaled drug compliance.

BACKGROUND The treatment of osteoporosis among postmenopausal women represents a major public health challenge since long-term therapy is needed to prevent fractures and chronic disability. OBJECTIVES To assess compliance with osteoporosis drug therapy among Israeli postmenopausal women treated with either a bisphosphonate (alendronate) or a selective estrogen receptor modulator (raloxifene);...

This is the first quantitative analysis of data from urine drug tests for compliance to treatment medications and abstinence from drug abuse across "levels of care" in six eastern states of America. Comprehensive Analysis of Reported Drugs (CARD) data was used in this post-hoc retrospective observational study from 10,570 patients, filtered to include a total of 2,919 patients prescribed at lea...

Urine drug screening can detect cases of drug abuse, promote workplace safety, and monitor drugtherapy compliance. Compliance testing is necessary for patients taking controlled drugs. To order and interpret these tests, it is required to know of testing modalities, kinetic of drugs, and different causes of false-positive and false-negative results. Standard immunoassay testing is fast, cheap, ...

BACKGROUND Chronic hepatitis C infection is common in drug users. Treatment of injectors is possible under controlled conditions, but many have not yet been included in treatment programmes as there are concerns about their ability to comply with therapy. It is not known which factors influence compliance. AIM To examine the hypothesis that active drug users would comply with anti-viral thera...

Canada's Patent Register is a tool created by the Patented Medicines (Notice of Compliance) Regulations to help innovators protect their inventions relating to pharmaceuticals. This tool exists at the intersection between the intellectual property and drug approval regimes. By listing a patent on the Patent Register, an innovator can prevent a generic manufacturer from entering the marketplace ...

The assessment of therapeutic compliance is commonly done by either indirect method or direct method. In indirect method, the assessments are done by indirect measurement of parameters such as discussion with patients and pill counts at intervals during the treatment which don’t measure the drug concentration in a matrix such as blood or urine. In direct method, the assessments which rely upon ...

the aim of the current study was to design a porous osmotic pump–based drug delivery system for controlling the release of buspirone from the delivery system. the osmotic pump was successfully developed using symmetric membrane coating. the core of the tablets was prepared by direct compression technique and coated using dip-coating technique. drug release from the osmotic system was studied us...