Introduction Prediction of fluid responsiveness (FR) is a critical step in management of patients with septic shock. Using ultrasound in detection of inferior vena cava (IVC) diameters and collapsibility is established in mechanically ventilated patients; however its use in spontaneous breathing patients is still controversial [1]. Few studies reported a correlation between internal jugular vei...

In this paper we determine the threshold for d-collapsibility in the probabilistic model Xd(n, p) of d-dimensional simplicial complexes. A lower bound for this threshold p = ηd n was established in [?], and here we show that this is indeed the correct threshold. Namely, for every c > ηd, a complex drawn from Xd(n, c n ) is asymptotically almost surely not d-collapsible.

Ultrasound provides a rapid method of evaluating the emergency patient at the bedside by the treating physician. Besides being advantageous in eliminating or supporting a differential diagnosis in an emergency patient, bedside ultrasound can also rapidly evaluate physiology. This articles describes such a use of bedside ultrasound, the evaluation of the inferior vena cava size and collapsibilit...

The PAT family proteins, named after perilipin, adipophilin, and the tail-interacting protein of 47 kDa (TIP47), are implicated in intracellular lipid metabolism. They associate with lipid droplets, but how is completely unclear. From immunofluorescence studies, they are reported to be restricted to the outer membrane monolayer enveloping the lipid droplet and not to enter the core. Recently, w...

A quantitative description of the dynamics of droplet motion has been a long-standing concern in electrowetting research. Although many static and dynamic models focusing on droplet motion induced by electrowetting-on-dielectric (EWOD) already exist, some dynamic features do not fit these models well, especially the dynamic saturation phenomenon. In this paper, a dynamic saturation model of dro...

Accurate and precise nucleic-acid quantification is crucial for clinical and diagnostic decisions, as overestimation or underestimation can lead to misguided treatment of a disease or incorrect labelling of the products. Digital PCR is one of the best tools for absolute nucleic-acid copy-number determination. However, digital PCR needs to be well characterised in terms of accuracy and sources o...

Water droplet impact on surfaces is a ubiquitous phenomenon in nature and industry, where the time of contact between droplet and surface influences the transfer of mass, momentum and energy. To manipulate and reduce the contact time of impacting droplets, previous publications report tailoring of surface microstructures that influence the droplet - surface interface. Here we show that surface ...

The transient response of a millimeter-sized sessile droplet under electrical actuation is experimentally investigated. Under DC actuation, the droplet spreading rate increases as the applied voltage is increased due to the higher electrical forces induced. At sufficiently high DC voltages, competition between the electrical actuation force, droplet inertia, the retarding surface tension force ...

During sedation and recovery the airway of children with obstructive sleep apnea is vulnerable to collapse. This vulnerability arises from both an inherent collapsibility of the pharyngeal airway in these children and a heightened sensitivity to sedative and anesthetic agents. Pharmacologic and nonpharmacologic support may be required to defend pharyngeal airway patency in children with obstruc...

Deformation of a rotating two-lobed liquid droplet was simulated numerically by solving the three-dimensional Navier-Stokes equations using the level set method. The two-lobed droplet was formed by rotating a spherical droplet; the droplet changed its shape from the sphere to the rotating ellipsoid, and to the two-lobed shape. It was found that the time histories of the deformation of two-lobed...