Local scouring in the downstream of hydraulic structures is one of the important issues in river and hydraulic engineering, which involves a lot of costs every year, so the prediction of the rate of scour is important in hydraulic design. Side weirs are the most important of hydraulic structures that are used in passing flow. This study investigate the scouring due to falling jet from side weir...

The transition to continuous biomanufacturing is considered the next step reduce costs and improve process robustness in biopharmaceutical industry, while also improving productivity product quality. platform production for monoclonal antibodies (mAbs) eligible processing lower manufacturing due patent expiration subsequent growing competition. One of critical quality attributes interest during...

Core RNA-processing reactions in eukaryotic cells occur cotranscriptionally in a chromatin context, but the relationship between chromatin structure and pre-mRNA processing is poorly understood. We observed strong nucleosome depletion around human polyadenylation sites (PAS) and nucleosome enrichment just downstream of PAS. In genes with multiple alternative PAS, higher downstream nucleosome af...