Abstract Introduction: although pediatric patients have comparatively fewer cases of COVID-19, children with Down Syndrome exhibit comorbidities such as immunodeficiency, diabetes and, in this perspective, are considered a population at risk for severe COVID-19. In addition, the literature also points to an unfavorable perspective on co-infection Mycobacterium tuberculosis, important comorbidit...

disorder in re-methylation process of homocysteine to methionine due to mutation in betaine homocysteine methyltransferase enzyme (bhmt) coding gene, leads to decrease in s-adenosyl methionine (sam) synthesis which takes part in dna methylation as a methyl donor. as a result, it can promote hypo-methylation of dna, chromosome instability, and chromosome missegregation, which in turn is one of t...

Mothers of a child with intellectual disability (ID) have more psychiatric disorders after the birth of their child than other mothers. However, it is unclear if this is because they have more psychiatric disorders before the birth or if the increase is related to the burden of caring for the child. We aimed to calculate the rate of new psychiatric disorders in mothers after the birth of their ...

BACKGROUND Knowledge of sitting and standing performance in a total population of children with cerebral palsy (CP) is of interest for health care planning and for prediction of future ability in the individual child. In 1994, a register and a health care programme for children with CP in southern Sweden was initiated. In the programme information on how the child usually sits, stands, stands u...

Down Syndrome Parents' Support Group Siriraj Hospital was established on February 14, 1993. It consists of a group of pediatricians, nurses, parents of children with Down Syndrome (DS) who received care at the Genetics Clinic, Division of Medical Genetics, Department of Pediatrics, Faculty of Medicine Siriraj Hospital. The objective is to educate parents with DS children whose diagnosis of DS g...

In the 1970s, they were a number of cases where children born with disabilities were denied lifesaving surgeries. In some cases, doctors left the decision totally up to the parents who refused the surgery because they were worried about the financial and emotional burden of raising the child. Many of these cases involved children with Down Syndrome (or Trisomy 21) with esophagheal and/or gastro...