The G-proteins which regulate hormonal turnover of phosphoinositide (PI) in human umbilical vein endothelial cells have been investigated. A 40-41 kDa doublet present in the membranes of these cells was selectively ADP ribosylated by pertussis toxin (PTx), and this doublet was Gi alpha 2 and Gi alpha 3 according to immunoblotting with specific antisera. By contrast, a doublet of 24-26 kDa prote...

The decay KL → πνν is an excellent probe of the nature of CP violation. It is almost entirely CP-violating, and hadronic uncertainties are negligible. Experiments which hope to detect the decay are currently being planned. We calculate the decay rate in several extensions of the standard model Higgs sector, including the Liu-Wolfenstein two-doublet model of spontaneous CP-violation and the Wein...

The two peaks of the vacuum Rabi splitting behave like simple harmonic oscillators for very weak excitation. The transmission spectrum of a cavity filled with two-level atoms shows this doublet at low values of the driving intensity, but only a single peak at high values. The evolution from a doublet to a singlet is governed by the anharmonic response of the system as the driving intensity incr...

Knowledge-based contact potentials have been popularly used in protein structure modeling. In this paper, we present a coarse-grained, context-dependent contact potential where the influences on inter-residue contacts from neighboring residues are taken into account. In particular, statistics of singlet-singlet, singlet-doublet, singlet-triplet, and doublet-doublet interactions are derived from...

We present a class of models with a third generation seesaw mixing with new vector-like weak-doublet quarks. We analyze a low-energy phenomenology and present several strong dynamics, high-energy realizations of these models. In the Topcolor type scenario, named Top-Bottom Color, we obtain an effective, composite two Higgs doublet model where the third generation isospin splitting is introduced...

Proposed herein is an alternative photonic scheme for the generation of a doublet UWB pulse, which is based on the nonlinear polarization rotation of an elliptically polarized probe beam. The proposed scheme is a modified optical-fiber Kerr shutter that uses an elliptically polarized probe beam together with a linearly polarized control beam. Through theoretical analysis, it was shown that the ...

When tubulins obtained from particular microtubules of the sea urchin (ciliary doublet A tubules, flagellar doublet microtubules, and mitotic microtubules) are analyzed by electrophoresis in a polyacrylamide gel system containing sodium dodecyl sulfate and urea, heterogeneity of the alpha subunit, and differences between the tubulins are revealed. The alpha subunit of tubulin from mitotic appar...

We aim to evaluate the efficacy and safety of paclitaxel-based doublet intravenous chemotherapy (IVC) with and without intraperitoneal chemotherapy (IPC) as the first-line treatment in advanced gastric cancer (AGC) with peritoneal metastasis (PM). 173 AGC patients with peritoneal metastasis were enrolled. All patients received paclitaxel-based doublet systemic chemotherapy Among them, 117 patie...

The ground and low-lying electronic states of the 1,3,5-tridehydrobenzene triradical are characterized by electronic structure calculations. It is found that the ground state is the A1 doublet of C2v symmetry. Another doublet state lies 0.1–0.2 eV higher in energy, and the lowest quartet state of D3h symmetry is 1.2–1.4 eV higher in energy. Both doublets are degenerate at D3h geometries and und...