Age-related maculopathy (ARM) remains a poorly understood degeneration. To discover new pathways using contemporary genomics, proteomics, and immunohistochemistry, validate emerging animal models, and validate new imaging modalities, human tissues obtained from donor eyes will be essential to ARM research for the foreseeable future. Because fundus appearance is the clinical diagnostic lingua fr...

BACKGROUND Oocyte donation is a popular treatment option among women with ovarian dysfunction. Little is known about the amount of information recipients have about their donors and if the amount of information the couple has relates to their plans to disclose. The purpose of this study was to assess the amount of information recipients had about their donors and their disclosure plans. METHO...

Logistic regression methods were used to analyse the influence of donor and storage factors on the quality of c~meas stored by organ culture in the Bristol eve bank in 1991. Averaae donor a(18 was 57 vears fsd 22. n=2770) -and time from death to en~cleation v& 8 hours (&I 7, n&782): Corneas were placed into organ culture within 27 houra (sd 10, n+2550) of donor death and were stored for 22 days...

Logistic regression methods were used to analyse the influence of donor and storage factors on the quality of c~meas stored by organ culture in the Bristol eve bank in 1991. Averaae donor a(18 was 57 vears fsd 22. n=2770) -and time from death to en~cleation v& 8 hours (&I 7, n&782): Corneas were placed into organ culture within 27 houra (sd 10, n+2550) of donor death and were stored for 22 days...

DONOR material for corneal grafting is not readily available. In exploring all sources, it was thought that one could use material which would otherwise be wasted if it were possible to cut satisfactory lamellar grafts from excised corneae. The attachment to be described is the result of experiments conducted with this purpose in view. The idea originated from a desire to use corneae from eyes ...

purpose: to evaluate the influence of donor characteristics (age, death-to-preservation time, preservation-to-surgery time, graft rating, and endothelial cell features) on clinical outcomes following deep anterior lamellar keratoplasty (dalk) in patients with keratoconus. methods: in this retrospective study, 290 consecutive keratoconic eyes underwent dalk using donor corneas of different quali...

To fabricate donor corneal substitutes based on carbodiimide cross-linked porcine collagen, to study their in vitro and in vivo properties, and to elaborate new implantation techniques for the donor corneal collagen-based substitutes, this study had been performed. Bioengineered substitutes of corneal stroma (BSCS) were fabricated by cross-linking porcine type I collagen with 1-ethyl-3-(3-dimet...

PURPOSE To evaluate the association of serum factors with the severity of diabetic retinopathy and to assess their presence in retinal tissue obtained at autopsy. METHODS The following serum factors of 93 subjects were examined at the National Eye Institute (NEI) clinical center: the chemokines regulated on activation, normal T-cell expressed and presumably secreted (RANTES)/CCL5, epithelial ...

background and objectives: tetanus and diphtheria are vaccine-preventable, infectious diseases with significant morbidity and mortality. immunization by the diphtheria and tetanus toxoid (dt) has been applied in iran for almost 50 years. however, there are very few data about the rate of immunity to these diseases in the adult population. the humoral immunity to tetanus and diphtheria among blo...

Report on a successful clinical case of a corneal penetrating keratoplasty using inadvertently a corneal graft that had undergone laser assisted in situ keratomileusis (LASIK). Review of a clinical case of a patient of the Cornea Department of the "Hospital Oftalmológico de Sorocaba" who underwent a penetrating keratoplasty (PK) to correct keratoconus in his left eye. A corneal graft from a don...