Deoxynivalenol (DON) is one of the most common contaminants of various foodstuffs. A biotransformation system was used in order to lessen the toxicity of DON. A strain of Aspergillus (NJA-1) was isolated from soil and cultured in an inorganic salt medium containing DON. Bt2a/Bt2b primers were used to amplify the beta-tubulin gene of NJA-1. Sequence analysis the PCR product and morphology observ...

Mycotoxin contamination associated with head blight of wheat and other grains caused by Fusarium culmorum and F. graminearum is a chronic threat to crop, human, and animal health throughout the world. One of the most important toxins in terms of human exposure is deoxynivalenol (DON) (formerly called vomitoxin), an inhibitor of protein synthesis with a broad spectrum of toxigenicity against ani...

a r t i c l e i n f o Little is known about the distribution and dynamics of dissolved organic nitrogen (DON) within Arctic Ocean surface waters, though seasonal inputs from both rivers and marine phytoplankton production are likely important. Here we combine multiple datasets to provide the first quasi-synoptic view of DON concentrations in the summertime Arctic Ocean Polar Surface Layer (PSL)...

Deoxynivalenol (DON) has various toxicological effects in humans and pigs that result from the ingestion of contaminated cereal products. This study was conducted to investigate the protective effects of dietary supplementation with glutamic acid on piglets challenged with DON. A total of 20 piglets weaned at 28 d of age were randomly assigned to receive 1 of 4 treatments (5 piglets/treatment):...

This study aimed to discover potential biomarkers for dioxynivalenol (DON) intoxication. B6C3F1 male mice were orally exposed to 0.83, 2.5 and 7.5 mg/kg body weight (bw) DON for 8 days and the differential protein expressions in their blood plasma were determined by SELDI - Time-of-Flight/Mass Spectrometry (TOF/MS) and the immunoglobulins (Igs) G, A, M and E in the serum were investigated. 11.7...

background: deoxynivalenol (don) is a mycotoxin produced mainly by fusarium graminearum in grains such as wheat and maize. the aim of this study was to evaluate the inhibitory effects of citrus flavanones including, naringin (nar), hesperidin (hes), and neohesperidin (neo) on deoxynivalenol production using response surface methodology (rsm). methods: the studied flavanones were extracted from ...

Deoxynivalenol (DON) is a secondary metabolite of Fusarium culmorum and Fusarium graminearum and is one of the most common mycotoxin contaminants of wheat, barley, maize, and cereal-based food products (Canady et al., 2001; Schothorst and van Egmond, 2004). Like other trichothecenes, DON induces a spectrum of effects in farm and laboratory animals including emesis (DON has the trivial name ‘‘vo...

Four experiments were conducted to investigate the effects of deoxynivalenol (DON) from naturally contaminated dried distillers grains with solubles (DDGS) and the efficacy of feed additives in nursery pig diets. In Exp. 1, 180 pigs (10.3 ± 0.2 kg BW) were fed 1 of 5 diets for 21 d. Diets were 1) Positive Control (PC; < 0.5 mg/kg DON), 2) Negative Control (NC; 4 mg/kg DON), 3) NC + 0.10% Biofix...

fusarium culmorum which is considered as the causal agent of fusarium head blight, can produce deoxynivalenol (don), nivalenol (niv) and their acetylated derivatives. this study has been assessed in order to detect the tri13 gene using primer pairs tri13donr/tri13f and tri13r/tri13nivf, to investigate the potential of f. culmorum isolates in the production of don and niv in west azarbayjan prov...