Infection of domestic rabbits with cottontail rabbit papillomavirus (CRPV) causes local papillomas which progress to carcinomas in more than 80% of cases. This animal model system therefore allows the identification of molecular mechanisms required for the induction and progression of epithelial tumors. The viral E2 protein stimulates both viral DNA replication and transcription, and these func...

Successful elimination of helminthic diseases, as well their further prevention, is possible only under the condition carrying out a complex organizational and economic, veterinary sanitary, special anti-parasitic measures, which must necessarily include disinfestation places where animals are kept, environmental objects. It necessary to establish ability modern chemical agents harm certain typ...

Fascioliasis is a parasitic disease of domestic ruminants that occurs worldwide. The lymnaeid intermediate hosts of Fasciola hepatica include Lymnaea columella, which is widely distributed in Brazil. A colony of L. columella from Belo Horizonte, MG, was reared in our laboratory to be used in studies of the F. hepatica life cycle, the intermediate host-parasite relationship and development of an...

Millions of domestic and wild European rabbits (Oryctolagus cuniculus) have died in Europe, Asia, Australia and New Zealand during the past 17 years following infection by Rabbit haemorrhagic disease virus (RHDV). This highly contagious and deadly disease was first identified in China in 1984. Epidemics of RHDV then radiated across Europe until the virus apparently appeared in Britain in 1992. ...

PURPOSE To describe a safe percutaneous method of transauricular endovascular access in small and large animals that uses basic catheter-based interventional skills and renders surgery and general anesthesia with intubation unnecessary. MATERIALS AND METHODS Twenty New Zealand White rabbits and five domestic juvenile swine were used in the experiments. Animals were restrained in the supine po...

Viral haemorrhagic disease (VHD) is a new and severe infectious disease of rabbits, with a high rate of morbidity and mortality. The disease occurs throughout the year, affecting only adult rabbits and not other domestic animals, fowls or laboratory rodents. The transmission is horizontal, by direct or indirect contact, and through all routes. There is no evidence of congenital infection or bio...

anti-human globulin was produced in iranian rabbits and goat by using human o serum mixed with freund's adjutants (complete or incomplete) for immunizing the animals. a titer of 1.4096 was obtained in rabbit and a titer of 1.2056 was obtained in goat. quality-and quantity-wise, goat's serum appeared to be better than rabbit's serum.

in the present study, the effects of intracerebroventricular (icv) administration of normal saline (control), histamine, mepyramine (a histamine h1-receptor antagonist) and ranitidine (a histamine h2-receptor antagonist) were investigated on the formalin-induced pain in rabbits. subcutaneous (sc) injection of a formalin (100 μl, 5%) solution into the ventral surface of the right hind paw was pe...

Domestic cats and other Felidae species are known to excrete three unusual amino acids in their urine; felinine, isovalthine, and isobuteine. Felinine (2-amino-7-hydroxy-5, 5-dimethyl-4-thiaheptanoic acid) was discovered in 1951 and is unique to certain Felidae species including the domestic cat (1). Isovalthine (2-amino-5-carboxy-6-methyl-4-thiaheptanoic acid) was found in the urine of healthy...

purpose: to evaluate the safety of different doses of intravitreal bevacizumab in rabbit eyes. methods: twelve eyes of 6 rabbits underwent intravitreal injection of 5, 7.5 and 10 mg of bevacizumab. in each rabbit, one eye was considered for bevacizumab injection and the fellow eye served for either placebo injection or observation. all eyes were examined before and 1, 2, 3, 7, 14 and 28 days af...