نتایج جستجو برای: dna biosensor

تعداد نتایج: 515602  

2008
Fabiane C. de Abreu Francine S. de Paula Danielle C. M. Ferreira Valberes B. Nascimento Alexandre M. C. Santos Marcelo M. Santoro Carlos E. Salas Julio C. D. Lopes Marília O. F. Goulart

The in situ DNA-damaging capacity of berenil (1) has been investigated usingan electrochemical approach employing double stranded (ds) DNA-modified glassy carbonelectrode biosensors. Electrochemical voltammetric sensing of damage caused by 1 todsDNA was monitored by the appearance of peaks diagnostic of the oxidation of guanineand adenine. When 1 was incorporated directly onto the biosensor sur...

Journal: :Biosensors & bioelectronics 2009
Joo-Myung Ahn Ee Taek Hwang Chul-Hee Youn Danusia L Banu Byoung Chan Kim Javed H Niazi Man Bock Gu

We report on a novel approach to predict the mode of genotoxic action of chemicals using a series of DNA damage specific bioluminescent bacteria. For this, a group of seven different DNA damage sensing recombinant bioluminescent strains were employed. Each of these strains was tested against model DNA damaging agents, such as mitomycin C (MMC), 1-methyl-1-nitroso-N-methylguanidine (MNNG), nalid...

Journal: :Journal of Pharmaceutical and Biomedical Analysis 2002

Journal: :Biosensors and Bioelectronics 2021

MicroRNAs are widely studied as circulating biomarkers for early stage diagnosis of several diseases. Detection and quantification miRNAs is currently performed through complex time consuming procedures. Herein we demonstrate a rapid, multiplex, one-pot detection method based on two-step amplification the signal measured by Reflective Phantom Interface (RPI) label-free optical biosensor. We ach...

2015
Yan Lei Fan Yang Lina Tang Keli Chen Guo-Jun Zhang

Due to the nearly identical phenotypes and chemical constituents, it is often very challenging to accurately differentiate diverse species of a Chinese herbal genus. Although technologies including DNA barcoding have been introduced to help address this problem, they are generally time-consuming and require expensive sequencing. Herein, we present a simple sequencing-free electrochemical biosen...

Journal: :Journal of the American Chemical Society 2013

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