This Article contains an error in panel B of Figure 4, where the 60 minute PMA stimulation results for 'DN-AP180' cannot be clearly seen. The correct Figure 4 appears below as Figure 1.

Let AN be an N-point set in the unit square and consider the Discrepancy function DN(~x) ≔ ♯ ( AN ∩ [~0, ~x) ) −N|[~0, ~x)|, where ~x = (x1, x2) ∈ [0, 1], [0, ~x) = ∏2 t=1[0, xt), and |[~0, ~x)| denotes the Lebesgue measure of the rectangle. We give various refinements of a well-known result of (Schmidt, 1972) on the L∞ norm of DN. We show that necessarily ‖DN‖exp(Lα) & (logN)1−1/α , 2 ≤ α < ∞ ...

A b st r a c t In th is papa -w e propose a new w avelet-ba d f uzzy model ing using a DN A coding method . General ly , it is wel l M om that the DN A coding method is more diverse in the know ledge expre ssion and better in the opt im izat ion P Hot¤tnm Ä £ an me genetalgor ithm (GA ) because i t can encode mom plent i ful genet ic informations bascd on the biological DN A M e proposed mcthod...

A growing body of evidence indicates that the renal proximal tubular epithelial cell (PTEC) plays an important role in the pathogenesis of diabetic nephropathy (DN). Microalbuminuria that intensifies over time to overt proteinuria, a hallmark of DN, is already known to activate the PTEC to induce tubulointerstitial inflammation. In addition to proteins, a number of diabetic substrates including...

Vol. 26 No. 4, 2014 547 Received June 4, 2013, Revised September 9, 2013, Accepted for publication September 13, 2013 Corresponding author: Seok-Jong Lee, Department of Dermatology, Kyungpook National University Hospital, 130 Dongdeok-ro, Jung-gu, Daegu 700-721, Korea. Tel: 82-53-420-5838, Fax: 82-53-426-0770, E-mail: [email protected] This is an Open Access article distributed under the terms...

OBJECTIVES Diabetic nephropathy (DN) is a major leading cause of kidney failure. Recent studies showed that serological microRNAs (miRs) could be utilized as biomarkers to identify disease pathogenesis; the DN-related miRs, however, remained to be explored. METHODS A prospective case-control study was conducted. The clinical significance of five potential miRs (miR-21, miR-29a, miR-29b, miR-2...

BACKGROUND Many synthesized drugs with clinical severe side effects have been used for diabetic nephropathy (DN) treatment. Therefore, it is urgent and necessary to identify natural and safe agents to remedy DN. Timosaponin B-II (TB-II), a major steroidal saponin constituent in Anemarrhena asphodeloides Bunge, exhibits various activities, including anti-inflammatory and hypoglycemic functions. ...

Diabetic nephropathy (DN) as the primary cause of end-stage kidney disease is a common complication of diabetes. Recent researches have shown the activation of nuclear factor kappa light-chain enhancer of activated B cells (NF-κB) and NACHT, LRR and PYD domain-containing protein 3 (NLRP3) inflammasome are associated with inflammation in the progression of DN, but the exact mechanism is unclear....

BACKGROUND Constipation is a frustrating symptom affecting 3% of children worldwide. A fermented dairy product containing Bifidobacterium lactis strain DN-173 010 was effective in increasing stool frequency in constipated women. Our aim was to assess the effects of this product in constipated children. METHODS In this prospective randomized, double-blind, controlled trial, 159 constipated chi...

in this study, a commercially available kit in which propionylthiocholine is used as a substrate and a dibucaine solution to determine the variants of the enzyme were utilized. plasma cholinesterase activity of 151 patients who underwent different operations was measured during a period of six months. the mean±sd of the enzyme activity in 150 patients was 4.39±1.17 ku/l .. seventeen patients (1...