Electrospray ionization-ion trap mass spectrometry (ESI-MS) of imidazolidin-4-one peptidomimetic derivatives of the antimalarial drug primaquine (PQ) is reported. These compounds contain the imidazolidin-4-one moiety either at the N- or the C-terminal of a dipeptide backbone, thus respectively mimicking PQ-Amino Acid-Proline (PQAAPro) and PQProAA derivatives of PQ. Both the peptidomimetics and ...

Three dipeptides, belonging to the family of diketopiperazines (DKPs), were extracted from broth culture of the grapevine endophyte Alternaria alternata, and were tested against Plasmopara viticola on leaves of grapevine plants grown in greenhouse. DKPs, used at different concentrations (10(-3), 10(-4), 10(-5) and 10(-6)M) both singularly and in mixtures, demonstrated real effectiveness in inhi...

Kondisi perikanan demersal di perairan Taman Nasional Wakatobi (TNW) pada zona pemanfaatan khususnya Karang Kapota bisa dinyatakan padat tangkap, sehingga perlu dilakukan suatu penelitian mengenai perencanaan dan pengembangan melalui pendekatan sistem untuk mengurai permasalahan yang terjadi. Penelitian ini bertujuan mengidentifikasi karakteristik demersal, menganalisis stakeholders terlibat, m...

Abstract This study aimed to describe the characteristics and cultivation conditions of Thunnus albacares in Pelabuhan Perikanan Pantai (PPP, shore-port fisheries) Labuhan Lombok, East Lombok. Data was collected by a simple random sample using questionnaire for 30 fishing boats. Primary data interview with respondents field observation, while secondary obtained from records PPP BPS DKP, Results...

Semiconductor minerals are widely present on the surface of Earth, but their roles in process peptide formation from amino acids less studied, especially role different crystal facets origin life. In this research, High Performance Liquid Chromatography (HPLC), thermogravimetric analysis (TA/DTA), Nuclear Magnetic Resonance (NMR) and simulation calculations were used to study condensation glyci...

The main objective of the work discussed in this paper was evaluation of a chromatographic method for simultaneous determination of hydrochlorothiazide (HCTZ), lisinopril (L), and their impurities in pharmaceuticals. Chlorothiazide (CTZ) and disulfonamide (DSA), as potential impurities in hydrochlorothiazide, and diketopiperazine (DKP), as an impurity of lisinopril, were analyzed. The chromatog...

A new actinomycete strain designated TN256, producing antimicrobial activity against pathogenic bacteria and fungi, was isolated from a Tunisian Saharan soil. Morphological and chemical studies indicated that strain TN256 belonged to the genus Streptomyces. Analysis of the 16S rDNA sequence of strain TN256 showed a similarity level ranging between 99.79 and 97.8% within Streptomyces microflavus...

A moderately thermophilic, facultatively anaerobic, amylolytic bacterium was isolated from palm wine, a tropical alcoholic beverage that was sampled in Senegal. The cells were gram positive, catalase positive, non-spore forming, rod shaped, and slightly motile with peritrichous flagella. The strain which we examined did not possess cytochrome and produced L-(+)-lactate, acetate, ethanol, and fo...

Parallel manipulators are an interesting alternative to serial robots given the important mechanical and kinematic advantages offered. Nevertheless, they often present more complex and smaller workspaces with internal singularities (Altuzarra et al., 2004; Gosselin & Angeles, 1990). Thus, the workspace size, shape and quality are considered some of the main design criteria of these robots (Merl...