There remains no doubt that primary abscesses are due to a hematogenous spread due to bacteremia and secondary abscess occurs as a result of direct spread of infection from an adjacent structure [2,3]. A case of primary psoas abscess with spondylodiscitis was published earlier by us [4]. Hernández-Ros, et al. commented that all authors must use the recent classification criteria and accordingly...

A number of agents with different actions on the dopaminergic system have shown positive preliminary results. However, due to the limited number of trials, it is difficult to determine which one yields the most promising therapeutic outlook. Some appear to stand out (e.g. modafinil, disulfiram or the cocaine vaccine), although larger clinical trials are necessary to assess the effectiveness of ...

We report a man who developed oculogyric crisis one month after disulfiram intoxication. Brain MRI showed lesions involving bilateral globus pallidus and left substantia nigra. In our patient, neuronal discharges from pathologically reorganized basal ganglia circuit to the mid-brain ocular motor center might lead to tonic deviation of the eyes.

The biosynthetic enzyme peptidylglycine alpha-amidating monooxygenase catalyzes the formation of a variety of biologically active alpha-amidated peptides from respective COOH-terminal glycine-extended peptide precursors. Peptidylglycine alpha-amidating monooxygenase activity is dependent on copper, ascorbate, and molecular oxygen and is inhibited by the relatively selective copper chelator N,N-...