نتایج جستجو برای: distal clearance margin dcm

تعداد نتایج: 153700  

Journal: :Veterinary pathology 2005
A Tidholm L Jönsson

Dilated cardiomyopathy (DCM), characterized by chamber dilatation and myocardial systolic and diastolic dysfunction, is one of the most common heart diseases in dogs. The clinical diagnosis is based on findings on echocardiographic and Doppler examinations, with the active exclusion of other acquired or congenital heart diseases. However, the echocardiographic criteria for the diagnosis of DCM ...

Journal: :American journal of physiology. Endocrinology and metabolism 2016
Tao Bai Fan Wang Nicholas Mellen Yang Zheng Lu Cai

Diabetic cardiomyopathy (DCM) is the leading cause of mortality in diabetes. As the number of cases of diabetes continues to rise, it is urgent to develop new strategies to protect against DCM, which is characterized by cardiac hypertrophy, increased apoptosis, fibrosis, and altered insulin metabolism. The E3 ubiquitin ligases (E3s), one component of the ubiquitin-proteasome system, play vital ...

Journal: :Japanese heart journal 2002
Isao Nishi Keiji Ilda Satoru Kawano Tomoko Masumi Yuko Fumikura Sadanori Ohtsuka Shigeyuki Watanabe Iwao Yamaguchi

The pathogenesis of dilated cardiomyopathy (DCM) is unknown, but clinical evidence suggests that coronary vasospasm is associated with the development of DCM in some cases. In the present study, we aimed to clarify the prevalence of coronary vasospasm in patients with DCM, the characteristics of patients with DCM and coronary vasospasm, and the effects of anti-vasospastic agents on patients wit...

2017
Bingdi Yan Jin Ren Qinghua Zhang Rong Gao Fenglian Zhao Junduo Wu Junling Yang

Diabetic cardiomyopathy (DCM) is a common and severe complication of diabetes and results in high mortality. It is therefore imperative to develop novel therapeutics for the prevention or inhibition of the progression of DCM. Oxidative stress is a key mechanism by which diabetes induces DCM. Hence, targeting of oxidative stress-related processes in DCM could be a promising therapeutic strategy....

Journal: :Geosciences 2021

A key aspect on the evolution of rifted terranes and prospectivity overlying sedimentary basins is heat. Temperature determines deformation regime crustal mantle rocks and, thus, style rifting geometry rift basins. The generation hydrocarbons from organic-rich reservoir conditions depend primarily temperature. In this study, we model thermal–burial history southern Vøring Basin (Mid-Norway Marg...

Journal: :Cancer research 1983
A F Sobrero J R Bertino

Prior to their use in patients with hepatic metastasis of colon cancer, we studied the cell-killing effects of 5-fluorouracil, 5-fluoro-2'-deoxyuridine, 3',5'-dichloromethotrexate (DCM), and 5-fluoro-2'-deoxyuridine, 3',5'-dichloromethotrexate (DCM), and combinations of these fluoropyrimidines with DCM on a human colon carcinoma cell line (HCT-8). Sequential exposure of these cells to DCM follo...

Journal: :The Journal of heredity 2007
Ute Philipp Cornelia Broschk Andrea Vollmar Ottmar Distl

Dilated cardiomyopathy (DCM) is a common disease in humans and dogs. Large-breed dogs and especially Irish wolfhounds belong to the frequently affected breeds. Male Irish wolfhounds show a significantly higher prevalence of DCM than females. Therefore, we evaluated X chromosome markers for linkage with DCM as well as a human candidate gene on the X chromosome. A set of X chromosomal microsatell...

2017
Christopher R Cashman Ahmet Hoke

Following injury, distal axons undergo the process of Wallerian degeneration, and then cell debris is cleared to create a permissive environment for axon regeneration. The innate and adaptive immune systems are believed to be critical for facilitating the clearance of myelin and axonal debris during this process. However, immunodeficient animal models are regularly used in transplantation studi...

Journal: :American journal of physiology. Gastrointestinal and liver physiology 1999
Edith Hummler Jean-Daniel Horisberger

The epithelial Na+ channel (ENaC) controls the rate-limiting step in the process of transepithelial Na+ reabsorption in the distal nephron, the distal colon, and the airways. Hereditary salt-losing syndromes have been ascribed to loss of function mutations in the α-, β-, or γ-ENaC subunit genes, whereas gain of function mutations (located in the COOH terminus of the β- or γ-subunit) result in h...

Journal: :Journal of clinical pathology 1989
S S Cross A D Bull J H Smith

The proximal and distal bowel resection margins of 339 specimens of colorectal adenocarcinoma were examined for the presence of tumour. In only five cases was tumour found in a resection margin. In four of these cases macroscopic examination showed that the tumour extended to the resection margin. In the fifth case the tumour was present in the pericolic fat. These results and reported data on ...

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