objective: this study aimed to evaluate the non-compliance rate in patients with bipolar i disorder (bid). methods: the patients admitted to iran psychiatric hospital who were diagnosed as a case of the first episode mania of bipolar i disorder (dsm-iv-tr) by 2 psychiatrists followed by one of them in a longitudinal, prospective and naturalistic study. in the follow-up early non-compliance/irre...

background: fatty acids play various physiological roles in the organism; they are crucial for the structure of cell membranes, metabolic processes, transmission of nerve impulses and brain functions. in recent years, particular attention has been paid to the rich sources of omega‑3 for the treatment of many diseases, especially mental illnesses. the present study aimed to investigate the effec...

purpose: to report two cases of conversion disorder with unilateral psychogenic pseudoptosis. case reports: the first case was 21 years old man who developed sudden ptosis of his left eye, since 2 weeks ago. the patient had episodes of upper lid drooping during the last 7 months; the second case was a 10 years old girl with history of ptosis since 6 months, after viral conjunctivitis. all neuro...

background:  depression is the world’s fourth most prevalent health problem which is ‎associated with substantial mortality, direct medical cost, diminished life quality, and ‎significant physical and psychosocial impairment. this study aimed to investigate the ‎effect of psycho-educational intervention on the life quality of major depressive patients.‎ materials and methods:  sixty patients wh...

purpose : to determine the distribution of iris colors in the population of tehran and to assess possible associations between iris color and ocular disorder methods : through a stratified random cluster sampling approach, 160 clusters were selected in different municipality districts of tehran, and the approached households were invited to a clinic. after the initial interview, all participant...

vitamin b6 is a cofactor of various enzymes influencing numerous neurotransmitters in the brain such as norepinephrin, and serotonin . since these neurotransmitters influence mood , the aim the present work to evaluate the effect of vitamin b6 on depression and obsessive compulsive behavior when coadministred with clomipramine, fluoxetine, or venlafaxine. male mice weighing 25-30 g were used. t...

objective: the methylenetetrahydrofolate reductase (mthfr) gene polymorphism c677t is suspected to be a risk factor for psychiatric disorders, but it remains inconclusive whether the mthfr polymorphism c677t is imputed to vulnerability to schizophrenia and bipolar disorder. method: we prompted impetus to appraise this polymorphism in an iranian population. therefore, 90 patients with bipolar di...

both at11th edition of the international classification of diseases (icd-11) and in fifth edition of the diagnostic and statistical manual of mental disorders (fifth edition-dsm-5), have pointed out that attitudes and quality of sleep can be seriously impaired by post-traumatic stress disorder (ptsd). the present study was conducted to compare hostility and sleep disorders among nursing student...

cognitive appraisals of the trauma play a key role in children’s adjustment following a traumatic event, but how these appraisals develop is not well understood. cognitive models of posttraumatic stress disorder (ptsd) suggest that social support is a key influence on the development of appraisals, and we aimed to explore this relationship further. as predicted by cognitive models of ptsd, we h...

post traumatic stress disorder (ptsd) is a disorder of emotional and mental stress occurring as an outcome of injury or severe emotional shock. yoga may be useful in decrease of ptsd symptomology. new studies demonstrate that people suffering from ptsd can find actual relief with yoga. yoga decreases stress-induced allosteric load in three reactive systems of stress: the autonomic nervous syste...