OBJECTIVE To evaluate a multi-biomarker disease activity (MBDA) score, a novel index based on 12 serum proteins, as a tool to guide management of RA patients. METHODS A total of 125 patients with RA from the Behandel Strategieën study were studied. Clinical data and serum samples were available from 179 visits, 91 at baseline and 88 at year 1. In each serum sample, 12 biomarkers were measured...

In many medical treatment areas, the use of treatment targets has led to improved outcomes, including a reduction in end-organ damage. In rheumatology, appropriate targets appear elusive, although preventing joint damage, minimizing disability and improving mortality are end results on which most clinicians would agree. Sophisticated measures of disease activity, particularly in early disease, ...

isolated hematuria and its association with proteinuria, and urinary cast and systemic lupus erythematosus (sle) disease activity, and decision for renal biopsy is a dilemma for physician in sle patients. the aim of this study was to investigate 1. whether isolated hematuria is associated with active sle, 2. to determine duration between hematuria and proteinuria and urinary cast, and 3. to det...

conclusions this study indicated that health belief model contrasts could predict the risky behavior of university students due to heart disease. however, more researches are needed to verify the predictors of high risky behaviors in students. background disease preventing methods focus mostly on lifestyle factors such as physical activity, healthy diet and not smoking. previous studies verifie...

The geomagnetic activity index Kp is widely used but restricted by low time resolution (3-hourly) and an upper limit. To address this, new indices, Hpo, are introduced. Similar to Kp, Hpo expresses the level of planetary in units thirds (0o, 0+, 1−, 1o, 1+, 2−, …) based on magnitude disturbances observed at subauroral observatories. has a higher than Kp. 30-min (Hp30) 60-min (Hp60) indices prod...