Lipids and coumarin were extracted from cumaru seeds using Soxhlet extraction (SE) with ethanol (EtOH) ethyl acetate (EtOAc), scCO 2 , +EtOH +EtOAc, either in a single or sequential stages, PLE EtOH. ScCO +EtOAc provided yields 28% to 31%, independently of the conditions employed, provide top yield 38%, at 25 MPa 80 ºC. Extraction enhanced by three extractions, resulting 44.0% 56.5% for +EtOH, ...