Phrenic long-term facilitation (pLTF) is a serotonin-dependent form of pattern-sensitive respiratory plasticity induced by intermittent hypoxia (IH), but not sustained hypoxia (SH). The mechanism(s) underlying pLTF pattern sensitivity are unknown. SH and IH may differentially regulate serine/threonine protein phosphatase activity, thereby inhibiting relevant protein phosphatases uniquely during...

Senescence secretome was recently reported to promote liver cancer in an obese mouse model. Steatohepatitic hepatocellular carcinoma (SH-HCC), a new variant of HCC, has been found in metabolic syndrome patients, and pericellular fibrosis, a characteristic feature of SH-HCC, suggests that alteration of the tumor stroma might play an important role in SH-HCC development. Clinicopathological chara...

SH&E PROFESSIONALS HAVE OFTEN become victims of their own success in achieving regulatory compliance; many business executives view beyondcompliance spending as a fruitless exercise (Soyka and Feldman 61). Compounding this problem is the fact that SH&E professionals seldom use business models or speak in business terms. Safety jargon is often considered irrelevant and inconsistent with standard...

Copper concentrations were measured in a 65 samples marketed and collected in Croatia in summer 2012: meat samples (bovine, pig, sheep), meat products (sausages, pâté), fi sh and fi sh products and shellfi sh (mussels, oysters). Mean Cu levels were (mg/kg): all meat 0.77, sausages 0.69, pâté 2.24, fi sh 0.23, fi sh products 1.20, mussels 0.81, oysters 30.0. Signifi cant diff erences were found ...

1. The construction of T(A) is motivated by dualizing the fundamental group 7Ti(X) of a differentiable manifold X with a base point Xo. Let A be the -R-algebra of C functions on X equipped with the derivation d, which is the usual differentiation from A into the Amodule M = ÛA of C 1-forms on X. Recall that the shuffle algebra Sh(M) consists of the i£-module of the tensor algebra TR(M) and the ...

A mathematical model is considered to investigate the behavior of horizontally polarized shear waves (SH-waves) in fluid saturated porous medium sandwiched between heterogeneous half-spaces. Heterogeneity in the upper half-space is due to linear variation of elastic parameters, whereas quadratic variation has been considered for lower half-space. The method of separation of variables and Whitta...

OBJECTIVE Treatment of type 1 diabetes has been intensified aiming at normalizing blood glucose, which may increase the risk of severe hypoglycemia (SH). We aimed to compare the incidence of SH events in the four Nordic countries Denmark, Iceland, Norway and Sweden, and to assess the influence of hemoglobin A1c (HbA1c) and treatment modalities on the frequency of SH; particularly, to explore if...

OBJECTIVES To investigate the frequency of severe hypoglycemia (SH) and hypoglycemic coma during the first trimester of type 1 diabetic pregnancy and in the 4 months before gestation and to identify risk indicators predicting first trimester SH in a nonselected nationwide cohort of pregnant women with type 1 diabetes. RESEARCH DESIGN AND METHODS We conducted a longitudinal cohort survey in 27...

Uniaxial compressive and Brazilian tensile strengths (UCS and BTS) of rocks are considered important properties in the design of most the geotechnical projects that interact with rock such as slope stability and underground excavation. Measuring UCS and BTS using standard laboratory tests are time consuming, tedious and expensive. Moreover, it requires a large number of well-prepared rock cores...