نتایج جستجو برای: dimensional gels

تعداد نتایج: 419042  

Journal: :Journal of cellular physiology 2017
Asima Karim Andrew C Hall

Changes to chondrocyte volume/morphology may have deleterious effects on extracellular matrix (ECM) metabolism potentially leading to cartilage deterioration and osteoarthritis (OA). The factors controlling chondrocyte properties are poorly understood, however, pericellular matrix (PCM) weakening may be involved. We have studied the density, volume, morphology, and clustering of cultured bovine...

Journal: :The Journal of Cell Biology 1991
C E Klein D Dressel T Steinmayer C Mauch B Eckes T Krieg R B Bankert L Weber

The ability of cultured human fibroblasts to reorganize and contract three dimensional collagen I gels is regarded as an in vitro model for the reorganization of connective tissue during wound healing. We investigated whether adhesion receptors of the integrin family are involved. It was found that synthesis and transcription of the alpha 2 beta 1 integrin (but not of alpha 1 beta 1 or alpha 3 ...

Journal: :American journal of physiology. Lung cellular and molecular physiology 2014
Tetsu Kobayashi HuiJung Kim Xiangde Liu Hisatoshi Sugiura Tadashi Kohyama Qiuhong Fang Fu-Qiang Wen Shinji Abe Xingqi Wang Jeffrey J Atkinson James M Shipley Robert M Senior Stephen I Rennard

Matrix metalloproteinase-9 (MMP-9) is a matrix-degrading enzyme implicated in many biological processes, including inflammation. It is produced by many cells, including fibroblasts. When cultured in three-dimensional (3D) collagen gels, fibroblasts contract the surrounding matrix, a function that is thought to model the contraction that characterizes both normal wound repair and fibrosis. The c...

Journal: Nanomedicine Journal 2019

Objective(s): Normoxic MAGIC-f polymer gels are established dosimeters used for three dimensional dose quantifications in radiotherapy. Nanoparticles with high atomic number such as gold are novel radiosensitizers used to enhance doses delivered to tumors. The aim of this study was to investigate the effect of gold nanoparticles (GNPs) in enhancing percentage depth doses (PDDs) within the MAGIC...

Bijan Hashemi, Hossein khosravi Seyed Rabi Mahdavi

Introduction: Normoxic MAGIC-f polymer gels are established dosimeters used for three dimensional dos uantifications in radiotherapy. The high atomic number nanoparticles such as gold are nov adiosensitizers used to enhance doses delivered to tumors. The aim of this study was t vestigate the effect of gold nanoparticles (GNPs) in enhancing percentage depth doses (PDD ithin the...

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