Salmonids are a group of teleosts with a nonspecialized gustatory system. With the aim of describing the gustatory connections in a member of this group, we carried out tract-tracing experiments using the lipophilic carbocyanine dye 1,1'-dioctadecyl 3,3,3',3'-tetramethylindocarbocyanine perchlorate (DiI) in fixed brains of the rainbow trout (Oncorhynchus mykiss). The neural tracer was applied t...

B lymphocytes, purified from peripheral leucocytes from young normolipaemic humans, expressed and internalized low-density lipoprotein receptors (LDLR). The expression was assessed by a monoclonal anti-LDLR. The internalization of LDL was assessed by LDL labelled with 125I (125I-LDL) and 1,1'-dioctadecyl-3,3,3',3' tetramethyl-indocarboxycyanine perchlorate (LDL-DiI). The expression of LDLR, ass...

Abstract Background Pathophysiology of IBS is not well recognized; however, several studies have shown the possible relationship between diet and risk IBS. We assessed ability dietary inflammatory index (DII) to predict Methods The subjects were 155 cases 310 age- sex-matched healthy controls (aged ≥18 years). participants recruited from June, 2019 March, 2020. was recognized using Rome IV crit...

Several hypotheses have been proposed to explain the increase and sustained expression of pituitary thyrotropin (TSH) in the presence of elevated plasma thyroid hormone (TH) concentrations at metamorphic climax in amphibians. It has been proposed that the negative feedback of TH on TSH is inoperative until metamorphic climax, and that it is established at this time by the upregulation of pituit...

In this report we consider a class of the integral matrices H p and a class of the spectral matrix characteristics p ; p 0. The report contains the proofs of their basic properties. Using these properties, we formulate criterion for a matrix spectrum to belong to the closed half-plane fRee 0g and prove theorems about qualitative properties of solutions of systems of ordinary diierential equatio...

Butterfly wing patterns have long been a favorite system for studying the evolutionary radiation of complex morphologies. One of the key characteristics of the system is that wing patterns are based on a highly conserved ground plan of pattern homologies. In fact, the evolution of lepidopteran wing patterns is proposed to have occurred through the repeated gain, loss, and modification of only a...

1 Funds provided by an institutional grant of the Hewlett Foundation to the Center for Applied Economics (CEA) at the DII are greatly acknowledged.

Pan, Yu-Zhen, De-Pei Li, Shao-Rui Chen, and Hui-Lin Pan. Activation of -opioid receptors excites spinally projecting locus coeruleus neurons through inhibition of GABAergic inputs. J Neurophysiol 88: 2675–2683, 2002; 10.1152/jn.00298.2002. Stimulation of the noradrenergic nucleus locus coeruleus (LC) releases norepinephrine in the spinal cord, which inhibits dorsal horn neurons and produces ana...

Lipoprotein lipase (LPL), a key enzyme in lipoprotein triglyceride metabolism, produces a marked increase in the retention and uptake of all classes of lipoproteins by cultured cells. It was previously shown that two different receptors are involved in mediating the LPL effects: heparan sulfate proteoglycans (HSPG) and the low density lipoprotein (LDL) receptor-related protein/alpha 2 macroglob...

SCOPE First- and second-generation antipsychotics (FGAs and SGAs, respectively), both inhibit cholesterol biosynthesis and impair the intracellular cholesterol trafficking, leading to lipid accumulation in the late endosome/lysosome compartment. In this study we examined if curcumin, a plant polyphenol that stimulates exosome release, can alleviate antipsychotic-induced intracellular lipid accu...