نتایج جستجو برای: diffusion adc
تعداد نتایج: 167870 فیلتر نتایج به سال:
background: gliomas are the most common primary neoplasms of the central nervous system. relative cerebral blood volume (rcbv) could estimate high-grade gliomas computed with dynamic susceptibility contrast mr imaging which it is artificially lowered by contrast extravasation through a disrupted blood-brain barrier. objectives: our intent was to clarify the usefulness of diffusion-weighted magn...
UNLABELLED We assessed the performance of parametric fusion PET/MRI based on (11)C-choline PET/CT and apparent diffusion coefficient (ADC) maps derived from diffusion-weighted MRI for the identification of primary prostate cancer. METHODS (11)C-choline PET/CT and MRI were performed in 17 patients with untreated primary prostate cancer, followed by prostatectomy. Registration of in vivo imagin...
Diffusion-weighted magnetic resonance imaging (DW-MRI) is a novel imaging technique that reflects microscopic water diffusion using a pair of strong diffusion gradients. It was developed to map the apparent diffusion coefficient (ADC) (1). Parallel to the development of DW-MRI, there have been advances in Dynamic contrast-enhanced MRI (DCEMRI). Using the MRI signal and pharmacokinetic models, p...
PURPOSE Evaluate the usefulness of diffusion-weighted spatiotemporally encoded (SPEN) methods to obtain apparent diffusion coefficient (ADC) maps of fibroglandular human breast tissue, in the presence of silicone implants. METHODS Seven healthy volunteers with breast augmentation were scanned at 3 Tesla (T) using customized SPEN sequences yielding separate silicone and water (1) H images in o...
Diffusion-weighted magnetic resonance imaging (MRI) is frequently used clinically, and is available for the whole-body screening for tumors. The exact mechanism by which the apparent diffusion coefficient (ADC) value decreases in tumorous tissue remains unclear, although various theories have been proposed, including intracellular and extracellular factor theories. It is impossible to distingui...
PURPOSE To compare the capabilities of apparent diffusion coefficient (ADC) and normalized ADC using the pancreatic parenchyma as reference organ in the characterization of focal pancreatic lesions. PATIENTS AND METHODS Thirty-six patients with focal pancreatic lesions (malignant, n=18; benign tumors, n=10; focal pancreatitis, n=8) underwent diffusion-weighted MR imaging (DWI) at 1.5-Tesla us...
This paper reports on results of a multisite collaborative project launched by the MRI subgroup of Quantitative Imaging Network to assess current capability and provide future guidelines for generating a standard parametric diffusion map Digital Imaging and Communication in Medicine (DICOM) in clinical trials that utilize quantitative diffusion-weighted imaging (DWI). Participating sites used a...
The decay of brain water signal with b-factor in adult and newborn brains has been measured over an extended b-factor range. Measurements of the apparent diffusion coefficient (ADC) decay curves were made at 16 b-factors from 100 to 5000 s/mm(2) along three orthogonal directions using a line scan diffusion imaging (LSDI) sequence to acquire data from 0.09 ml voxels in a mid-brain axial slice. R...
PURPOSE To determine quantitative quality control procedures to evaluate technical variability in multi-center measurements of the diffusion coefficient of water as a prerequisite to use of the biomarker apparent diffusion coefficient (ADC) in multi-center clinical trials. MATERIALS AND METHODS A uniform data acquisition protocol was developed and shared with 18 participating test sites along...
The assessment of cancer and its metastases by means of functional imaging techniques may lead to a more reliable diagnosis and early knowledge of the treatment efficacy. Diffusion-weighted magnetic resonance imaging (MRI) represents a promising imaging tool for tissue characterization, prediction and evaluation of therapeutic response in oncology. In cases of liver disease, diffusion-weighted ...
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