We retrospectively identified 9 consecutive children, 3 males and 6 females (age 5.2 ± 6.3 years, range 1 day to 18 years), with known or suspected AVGs who underwent MR imaging, including SWI, at our institution between January 2007 and March 2011. On the SWI sequence, arterialized blood flow was considered to be present in the vein of Galen or its tributaries when these showed abnormal signal...

Previously, we introduced the best-expert problem, and we proved a O(ln K) mistake bound for the majority vote algorithm when a perfect expert exists, i.e., there is an expert that never makes mistakes. Now let us turn to the more realistic case where there is no perfect expert among the committee. We extend the majority vote algorithm with a confidence weight. At each round, we maintain a weig...

We report a new clinically relevant model of neonatal hypoxic-ischemic injury in a 10-day-old rat pup. Bilateral carotid artery occlusion and 8% hypoxia (1 to 15 mins, BCAO-H) was induced with varying degrees of injury (mild, moderate, severe), which was quantified using magnetic resonance imaging including diffusion-weighted and T2-weighted imaging at 24 h and 21/28 days. We developed a magnet...

While Distance Weighted Discrimination (DWD) is an appealing approach to classification in high dimensions, it was designed for balanced datasets. In the case of unequal costs, biased sampling, or unbalanced data, there are major improvements available, using appropriately weighted versions of DWD (wDWD). A major contribution of this paper is the development of optimal weighting schemes for var...

Recent evidence indicates that neural adaptations related to changes in task performance occur in not only gray matter brain regions but also the white matter fiber tracts that connect the gray matter regions with one another. Here, we propose a framework for linking individual differences in global properties of the brain’s anatomical connectivity, or connectome, to individual differences in t...

The application of geographically weighted regression (GWR) - a local spatial statistical technique used to test for spatial nonstationarity - has grown rapidly in the social, health and demographic sciences. GWR is a useful exploratory analytical tool that generates a set of location-specific parameter estimates which can be mapped and analysed to provide information on spatial nonstationarity...

conclusion these data indicate that while ce-mri will depict more positive results, there are cases in which dwi will show a positive result while ce-mri is negative. we suggest that the combination of these two imaging modalities might yield more positive results in diagnosing acute ms attack giving rise to a more accurate diagnosis. results ce-mri yielded positive results for 61 (87%) patient...

We describe some modelling and reconstruction methods for optical imaging in the macroscopic and mesoscopic regimes. Beginning with the basic model of radiative transport, we describe the diffusion approximation and its extensions. Some linear and nonlinear problems in diffuse optical imaging are outlined, together with some indications of current trends and future directions.