نتایج جستجو برای: differentiated neuroendocrine carcinoma

تعداد نتایج: 459233  

2011
Günter Klöppel

Gastroenteropancreatic neuroendocrine neoplasms (GEP-NENs) are composed of cells with a neuroendocrine phenotype. The old and the new WHO classifications distinguish between well-differentiated and poorly differentiated neoplasms. All well-differentiated neoplasms, regardless of whether they behave benignly or develop metastases, will be called neuroendocrine tumours (NETs), and graded G1 (Ki67...

Journal: :Turk patoloji dergisi 2013
Teresa Pusıol Maria Grazia Zorzi Doriana Morichetti Ayşegül Sari

INTRODUCTION Large cell neuroendocrine carcinoma (LCNC) is defined in the urinary bladder, as in other sites, as a high-grade neoplasm exhibiting neuroendocrine features at the H&E level, high mitotic activity and evidence of neuroendocrine differentiation by immunohistochemistry. We report a case of pure bladder LCNC with review of the literature. METHODS A 68-year-old male presented with gr...

2017
Fernando Collado-Mesa Jose M. Net Geetika A. Klevos Monica M. Yepes

Neuroendocrine tumors of the breast are very rare accounting for less than 0.1% of all breast cancers and less than 1% of all neuroendocrine tumors. Focal neuroendocrine differentiation can be found in different histologic types of breast carcinoma including in situ and invasive ductal or invasive lobular. However, primary neuroendocrine carcinoma of the breast requires the expression of neuroe...

Journal: :Memo – Magazine of European Medical Oncology 2022

Summary In the last decade, a number of genetic alterations in gastroenteropancreatic neuroendocrine neoplasms (GEP-NENs) have been identified. addition, differences tumor morphology as well proliferation index (Ki-67) or mitoses led to changes classification these neoplasms. According new World Health Organization (WHO) classification, GEP-NENs are now divided into two genetically and prognost...

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