Laser-Doppler flowmetry (LDF) is an outstanding tool to monitor blood flow in a continuous and non-invasive way. In this work, we study LDF at large interoptode spacing applied to a human bone model (i.e. tibia diaphysis). To that aim, we first performed an extensive set of Monte Carlo (MC) simulations for 10 and 25 mm interoptode spacing. Second, we have assembled a dedicated LDF instrumentati...

PURPOSE Women with breast cancer are at increased risk for femur fracture. Contributing factors include estrogen deficiency, cancer-related therapies, or direct bone involvement. This study examines fracture subtypes in women with prior breast cancer experiencing a femur fracture. METHODS Women age ≥50 years old with a history of invasive breast cancer who experienced a femur fracture were id...

UNLABELLED INTRODUCTION Nonossifying fibroma is a common fibrous bone lesion in children that occurs in the metaphysis of the long bones of the lower extremities. The lesion rarely leads to aneurysmal bone cyst, which is characterized as a blood-filled space. CASE PRESENTATION We present the case of a 13-year-old Japanese boy with a complaint of discomfort in the thigh and a small, well-de...

OBJECTIVE To analyze standardized uptake values (SUVs) using three different tube current intensities for attenuation correction on (18)FNaF PET/CT scans. MATERIALS AND METHODS A total of 254 (18)F-NaF PET/CT studies were analyzed using 10, 20 and 30 mAs. The SUVs were calculated in volumes of interest (VOIs) drawn on three skeletal regions, namely, right proximal humeral diaphysis (RH), righ...

more so than in other mammals of comparable size. Tardigrada (sloths) exhibit the most extreme condition, particularly among the largest forms, such as the giant ground sloths, with femoral expansion always associated with strong anteroposterior compression. Biomechanical indexes show that Tardigrada, among Xenarthra, plotted far from other mammals, except those adapted to peculiar environments...

Healing of injured cancellous bone is characterized by a transient stage of rapid bone formation throughout the traumatized bone volume, often followed by similarly rapid resorption. This is different from the slower diaphyseal healing via an external callus. We, therefore, hypothesized that antiresorptive treatment might have an earlier positive effect in cancellous bone healing than in diaphy...

INTRODUCTION The purpose of the study is to compare the effects of genistein, estradiol, estradiol/progesterone combination on the bone mineral density and biomechanical properties of ovariectomized rats' bone. METHODS 50 female adult Sprague-Dawley rats were divided into five groups. Bilaterally ovaeriectomy were performed in all groups except the sham-operated group. Groups were a sham-oper...

Since the in vitro and in vivo anti-osteoporotic effects of Pueraria mirifica (PM) in rodents have been verified, its activity in menopausal monkeys was evaluated as required before it can be applicable for human use. In this study, postmenopausal osteoporotic monkeys were divided into two groups (five per group), and fed daily with standard diet alone (PMP0 group) or diet mixed with 1000 mg/kg...

Background/Aim: Pathological fractures are rare, suspicious and in some cases mentioned as the first sign of a malignant tumor. We present an uncommon case with pathological fracture tibia diaphysis severe hyperparathyroidism. Case Report: report female patient who was referred to emergency department history progressively worsening pain lower left leg inability fully bear weight. No trauma or ...