BACKGROUNDS Maternal total weight gain during pregnancy influences adverse obstetric outcomes in singleton pregnancies. However, its impact in twin gestation is less understood. Our objective was to estimate the influence of total maternal weight gain on preterm delivery in twin pregnancies. METHODS We conducted a retrospective cohort study including diamniotic twin pregnancies with spontaneo...

We present a case of a 33-year-old pregnant woman who had a transvaginal ultrasound performed at week 9 of gestation. A dichorionic diamniotic twin pregnancy with symmetrically developing fetuses, was confirmed. Chromosomal defect markers (NT NB, DV TV) were analyzed in the first genetic test, performed according to the Fetal Medicine Foundation (FMF) criteria, and the double marker test was pe...

Little is known about the mechanism of CGG instability and the time frame of instability early in embryonic development in the fragile X syndrome. Discordant monozygotic twin brothers with the fragile X syndrome could give us insight into the time frame of the instability. We describe monochorionic diamniotic twin brothers with the fragile X syndrome who had different CGG repeats and different ...

The aim of this study was to assess the aorta-intima thickness (aIT) and serum metabolomic profile in selective intrauterine growth-restricted (sIUGR) monochorionic diamniotic (MCDA) twin fetuses presenting Doppler velocimetry alterations. Fetal abdominal aIT was measured by ultrasound at 32 weeks of gestation, enrolling 24 MCDA twin fetuses (8 sIUGR and 16 controls). sIUGR twin fetuses were cl...

<b><i>Background:</i></b> Evidence to support a fortnightly scan protocol for monochorionic diamniotic (MCDA) pregnancies detect twin-twin transfusion syndrome (TTTS) is scarce. Also, TTTS-related mortality in an unselected cohort not well documented. Finally, common knowledge suggests that more frequent follow-up may pick up the disease at milder stage, but little known...

DESCRIPTION A 32-year-old woman, 22 weeks pregnant of monochorionic diamniotic twins, underwent fetoscopic laser coagulation of placental vascular anastomoses for a twin-to-twin transfusion syndrome (TTTS) Quintero stage III. Preoperative twoand three-dimensional ultrasound revealed the presence of an isolated unilateral cleft lip in the recipient twin (figure 1). At the time of surgery, fetosc...

OBJECTIVE To compare the fetal loss rate of monochorionic (MC) twin pregnancies according to their amnionicity. METHODS A retrospective review of all MC pregnancy outcomes in a tertiary centre. Pregnancy outcomes were compared for monochorionic monoamniotic (MCMA) versus monochorionic diamniotic (MCDA) pregnancies. RESULTS 29 MCMA and 117 MCDA twin pregnancies were identified. The overall f...

Blood chimerism in twins is known to occur through the transfer of hematopoietic stem cells between the fetuses via a common placenta. We present a case of blood chimerism in a dizygotic dichorionic twin pregnancy. The female twin was delivered at 34 weeks of gestation, and the male twin was stillborn. Pathologic examination confirmed dichorionic diamniotic placentas. The karyotype of the femal...

Background: Twin anaemia-polycythaemia sequence (TAPS) is a form of chronic twin-to-twin transfusion syndrome (TTTS) secondary to slow unidirectional blood flow across minuscule arteriovenous (AV) anastomoses. We present case presumed TAPS unusual, large, proximal Case report: Monochorionic diamniotic (MCDA) twins were born at 25+6 weeks gestation following intrauterine fetal demise. Ultrasound...