Statins have been reported to show preventive effect on nitrate tolerance in normal rats, but there are no reports on their effect in diabetic animals. In this study, diabetes was induced in male wistar rats by a single intraperitoneal injection of streptozotocin (45 mg/kg). Five groups of diabetic and five groups of normal rats were treated; groups 1 (of normal and diabetic rats) received ator...

Background: Osteoarthritis (OA) is a degenerative disease that can cause pain and limited function. One of the non-surgical treatments is intra-articular ozone injection. This study aimed to compare the effect of ultrasound-guided corticosteroid injection with ozone injection in patients with grade 3 osteoarthritis of the knee. Methods: This randomized, double-blind, clinical trial was carried...

background and objective: cardiovascular disorders continue to constitute major causes of morbidity and mortality in diabetic patients. in this study, the effect of chronic administration of tribulus terrestris (tt) feeding was studied on aortic reactivity of streptozotocin (stz)-diabetic rats and some underlying mechanisms were investigated.    materials and methods: male diabetic rats receive...

BACKGROUND Knee osteoarthritis is a disabling disease that costs billions of dollars to treat. Corticosteroid gives varying pain relief and costs $12 per injection, whereas ketorolac costs $2 per injection, per institutional costs. The aim of this study was to compare ketorolac with corticosteroid based on pain relief using patient outcome measures and cost data. METHODS A total of 35 patient...

background: poor response to various vaccines especially hepatitis b is common. the purpose of this study was to evaluate the effect of selenium on immune response against hepatitis b vaccine with accelerated method in insulin-dependent diabetes mellitus patients.methods: in this randomized clinical trial study, 62 insulin dependent diabetic patients were divided into case and control groups (e...

Multisite corticosteroid injection therapy is more effective in terms of pain relief, restoration motion, and functional status than single intra-articular for the treatment primary frozen shoulder (adhesive capsulitis).