نتایج جستجو برای: diabetic peripheral neuropathy

تعداد نتایج: 306419  

2017
M Rajasekaran

Peripheral neuropathy occurs as a component of several common and many rare diseases. It is heterogeneous in etiology, diverse in pathology, and varied in severity. Peripheral neuropathy is often overlooked, underestimated and not evaluated in day to day practice. The prevalence of neuropathy is well studied in patients with diabetes mellitus in most of the studies and other causes of neuropath...

Journal: :Diabetes 2002
Charlene E Hafer-Macko Frederick M Ivey Kymberly A Gyure John D Sorkin Richard F Macko

Human diabetic neuropathy is multifactorial in etiology, with ischemia as a final common pathology. Although impaired vascular endothelial cell function in diabetic microvascular injury is established, the role of thrombomodulin (TM)-dependent protein C antithrombotic mechanism in the pathogenesis of neuropathy is unclear. This neuropathologic case-control study investigated whether vascular en...

2006
Vinay Chaudhry James C. Stevens John Kincaid T. So

Surgical decompression at the site of anatomic narrowing has been promoted as an alternative treatment for patients with symptomatic diabetic neuropathy. Systematic review of the literature revealed only Class IV studies concerning the utility of this therapeutic approach. Given the current evidence available, this treatment alternative should be considered unproven (Level U). Prospective rando...

2009
Vijay Viswanathan Sharad pendsey Arun Bal

Some diabetic patients develop a diabetic peripheral neuropathy characterised by loss of sensation in the feet. Such patients have a high risk of injuries which often go unnoticed. Diabetic patients particularly those with neuropathy have abnormal pressure points under the feet. In these area, the skin gets thickened (called callus) which then becomes an ulcer. Chronic infection in the ulcer ul...

Journal: :iranian journal of diabetes and obesity 0
gholamreza shamsaei 1. neurology department, golestan hospital, ahvaz jundishapour university of medical sciences, ahvaz, iran nastaran madjdinasab 1. neurology department, golestan hospital, ahvaz jundishapour university of medical sciences, ahvaz, iran hajieh bibi shahbazian 2. diabetes research center, ahvaz jundishapur university of medical sciences, ahvaz, iran mehdi norouz sarvestani 1. neurology department, golestan hospital, ahvaz jundishapour university of medical sciences, ahvaz, iran armaghan moravej aleali 2. diabetes research center, ahvaz jundishapur university of medical sciences, ahvaz, iran

objective: diabetes mellitus is one of the most common endocrine diseases with micro-vascular complications and is a common cause of polyneuropathy. we studied the effect of enalapril on electrophysiologic criteria and clinical symptoms of patients with type ii diabetes and sensory neuropathy. materials and methods: a double blind study was conducted on 45 patients with type ii diabetes and neu...

1999
Andrew JM Boulton

Estimates of the prevalence of diabetic neuropathy range from 10% to 90% of the diabetic population, depending on the criteria used to define neuropathy. Diabetic neuropathy encompasses a wide range of abnormalities affecting both the peripheral and autonomic nervous systems and causes considerable injury and death. Neurologic complications occur equally in type 1 and type 2 diabetes mellitus, ...

2012
Niels Thomsen Anders Bjorkman Lars B. Dahlin

Diabetic neuropathy is the most common long-term complication of Type 1 and Type 2 diabetes, affecting approximately 10% within a year of diagnosis to 50% of subjects with diabetes for more than 25 years. Prevalence rates depend on diagnostic technique and the population under study (Dahlin et al., 2011; Rubino et al., 2007). Diabetic neuropathy associated with Type 1 diabetes tend to be more f...

2017
Ping-Hui Wang Cheng-Chang Yang Wei-Ren Su Po-Ting Wu Shun-Chien Cheng I-Ming Jou

PURPOSE To determine susceptibility to decompression surgery in diabetic and nondiabetic peripheral neuropathy using a chronic compression neuropathy model. MATERIALS AND METHODS Twenty-four streptozotocin-induced diabetic rats were randomly divided into three groups: group I, chronic compression of the left sciatic nerve for 4 weeks with decompression; group II, similar without decompression...

2011
Sylvia McAra

Background Peripheral sensory neuropathy is a common complication in diabetes. Neuropathy is the single most powerful risk factor for diabetic foot amputation. Often foot care efforts are thwarted by the phenomenon of inadvertent injury, from events which may appear to the clinician as chronic and ignorant self-neglect on the part of neuropathic clients. This study aimed to determine the propor...

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