BACKGROUND The TRPA1 ion channel modulates excitability of nociceptors, and it may be activated by compounds resulting from oxidative insults. Diabetes mellitus produces oxidative stress and sensory neuropathy. The authors tested the hypothesis that diabetes-induced endogenous compounds acting on the TRPA1 ion channel contribute to development and maintenance of mechanical hypersensitivity. M...

Diabetic macular edema represents one of the most important causes of visual morbidity in diabetes mellitus. The National Diabetes Information Clearinghouse estimates the prevalence of diabetes mellitus types 1 and 2 at 11.3% of the population above the age of 20, with an annual incidence of 1.9 million cases in the United States alone. In this population, the prevalence of diabetic macular ede...

CONTEXT The long-term outcome of persons with youth-onset type 2 diabetes mellitus has not been well described. OBJECTIVE To compare incidence of diabetic end-stage renal disease (ESRD) and mortality in Pima Indians with youth- and older-onset type 2 diabetes mellitus. DESIGN, SETTING, AND PARTICIPANTS Longitudinal population-based study conducted between 1965 and 2002 in Pima Indians from ...

Diabetic nephropathy can be identified as diabetes mellitus's furthermost significant complications. Tne End-Stage Renal Disease is also a result of diabetic nephropathy. The first-line therapy for patients with accompanied by proteinuria renin-angiotensin-aldosterone system inhibition. possible renoprotective effect evaluation valsartan/ sacubitril (ARNI) on model induced in rats compared ...

Visual evoked potentials (VEPs) were assessed in 50 adult type I (insulin-dependent) and 19 type II (noninsulin-dependent) diabetes mellitus patients and in 54 controls. P100 wave latency was significantly longer in diabetic patients (P less than .001). Twenty-eight percent of diabetic patients had P100 wave latencies above the normal range. There was no correlation between P100 latency and typ...

Introduction: COVID-19 pandemic is spread by droplet infectionwith symptoms of fever, cough,diarrhea,dyspnea, fatigue, myalgia, headache, anosmia and ageusia. Morbidity mortality higher amongelderly in patients with comorbidities especially Diabetes Mellitus(DM). Biomarkers inflammationare potential predictors for prognosis covid patients.Aim: To analyze the association NLR 19 diabetic status O...

Visual and auditory reaction times were studied in patients suffering from diabetes mellitus and age matched normal control subjects. Auditory reaction times were shorter than visual reaction times in control subjects as well as diabetic patients. In diabetic patients, there was significant prolongation of visual as well as auditory reaction times. Further studies of reaction times for various ...

Diabetes mellitus is considered a serious endocrine syndrome. The prevalence of diabetes mellitus in the general population is greater than 6%. Many herbal medicines have been recommended for the treatment of diabetic. The present study was carried out to investigate the effect of the alcoholic extract seeds of Coriandrum sativum L. on blood glucose in streptozotocin-induced diabetic rats. The ...

Diabetes mellitus is considered a serious endocrine syndrome. The prevalence of diabetes mellitus in the general population is greater than 6%. Many herbal medicines have been recommended for the treatment of diabetic. The present study was carried out to investigate the effect of the alcoholic extract seeds of Coriandrum sativum L. on blood glucose in streptozotocin-induced diabetic rats. The ...

We report a case of sudden thigh pain from spontaneous quadriceps necrosis, also known as diabetic myonecrosis, in a 28-year-old patient with poorly controlled diabetes mellitus. Diabetic muscle infarction is a rare end-organ complication seen in patients with poor glycemic control and advanced chronic microvascular complications. Proposed mechanisms involve atherosclerotic microvascular occlus...