today diabetes is one of the most common diseases in the world that affects half of the world population. today, the use of medicinal herbs especially green tea and cinnamon has been taken into consideration for relieving the symptoms of diabetes, but there were some different ideas about their effectiveness. so, this study was conducted to evaluate the effect of cinnamon and green tea extract,...

background: hyperglycemia is one of the important featurs of diabetes. in cell culture studies different methods are used to mimic the hyperglycemia condition. in this study we investigate response of human liver cancer cell line (hepg2) to high insulin, high glucose, and high insulin/ high glucose medium exposure. methods: hepg2 cells were settled in dmem+0.1% fbs or dmem free-serum medium wit...

obesity is a chronic disease that shows the most serious global health problems .it relates to the body fat .obesity is caused by an imbalance between energy intake and expenditure, this balance is regulated by genetic and environmental interactions. obesity, which is a risk factor for chronic diseases, has become epidemic in the developed countries. resistance to leptin hormone is one of the m...

background and objectives: type 2 diabetes is the most prevalent form of diabetes mellitus and is associated with a variety of complications. homocysteine is an important independent risk factor for atherosclerotic diseases in both diabetic and non diabetic subjects. the association between these two is still unclear. the aim of this study was to assess the serum homocysteine levels in uncompli...

metabolic syndrome and its pathological sequel, type 2 diabetes are considered as important global health problems. metformin is the most common drug prescribed for patients with this disorder. consequently, understanding the genetic pathways involved in pharmacokinetics and pharmacodynamics of this drug can have a considerable effect on the personalized treatment of type 2 diabetes. in this st...

mucormycosis is an invasive fungal infection caused by filamentous fungi of the mucoraceae family. the genera most commonly responsible are mucor or rhizopus. the disease occurs mostly in association with diabetic ketoacidosis. mucormycosis has an extremely high death rate even when aggressive surgery is done. death rates range from 25-85% depending on the body area involved.a case of rhinocere...

background apoptosis is a physiological mechanism of cell death and it can be triggered by a variety of internal and external stimuli. it has been indicated that some opium derivatives develop cell apoptosis. objectives the aim of this investigation was to evaluate the effect of opium addiction on ovary cell apoptosis in diabetic and non-diabetic wistar rats. materials and methods this experime...

conclusions it can be concluded that tempol can improve dyslipidemia and may decrease hyperglycemia in diabetes. it seems that antioxidants such as tempol can improve dyslipidemia and may decrease hyperglycemia in diabetes. results the blood glucose level increased following diabetes induction. the level of blood glucose in the diabetic receiving tempol group decreased compared to the control d...

background : joint proprioception plays an important role in limb movement and awareness of position sense. diabetes has a lot of complications such as lossof sensoryfunction, which canleadtoimpaired balance, thus the aim of this study to evaluated joint proprioception and balance in diabetic patients. methods: twenty type ii diabetic patients and20healthy controls participated in this case-con...

background & aim: solenostemon monostachyus has remain invincible in ibibio ethnomedicine for the management of numerous ailment including diabetes mellitus. many of these ethnomedicinal claims are yet to be pharmacologically verified. the purpose of this study therefore was to subject the extract/fractions of solenostemon monostachyus used in folkloric management of diabetes to scientific ...