Synthetic marijuana is an uptrending designer drug currently widely spread in the US. We report a case of acute deterioration of nonischemic left ventricular dysfunction after exposure to synthetic marijuana. This case illustrates the importance of history taking in cardiac patients and identifies a negative cardiovascular effect of synthetic marijuana known as K2, not yet well detected by urin...

In this issue of Neuron, Grayson et al. (2016) report how inhibition of amygdala impacts amygdalocortical and corticocortical functional connectivity. Their study predicts changes in functional brain topology, induced by pharmacologic modulation of neuroanatomical circuits using designer receptors exclusively activated by designer drugs (DREADDs), through virtual lesioning of amygdala in struct...

The reliability and performance of NMOSFET asymmetric LDD devices (with no LDD on the source side) are compared with that of conventional LDD devices. The results show that asymmetric LDD devices exhibit higher Idsat and larger Isub . To maintain the same hot-carrier lifetime, asymmetric LDD devices must operate at lower Vdd . For the same hot-carrier lifetime, we show that ring oscillators wit...

The severity of the incidents of recreational boats in Spain during 2011 is analyzed in terms of the region in which the crafts were registered. The data was obtained and coded from the damage reports of one of the main Spanish marine surveyors, source that has been used for the first time to our knowledge in the academic literature. About 1400 incidents are statistically compared in terms of l...

iii The thesis of Abdur Rafay is approved, and it is acceptable in quality and form for publication on microfilm and electronically:

The class of rate adaptation schemes based on linear Loss Dependent Decrease (LDD) policies is considered. A particular LDD policy, referred to as the history independent (hi)-LDD policy, is identified and studied here and some interesting properties are shown. Based on these properties it is possible to estimate the fair share and use it to adjust dynamically the control parameters so that a g...

This paper presents a first step towards a mixed-initiative tool for the creation of game maps. The tool, named Sentient World, allows the designer to draw a rough terrain sketch, adding extra levels of detail through stochastic and gradient search. Novelty search generates a number of dissimilar artificial neural networks that are trained to approximate a designer’s sketch and provide maps of ...

SI-Designer (Source Integrator Designer) is a designer support tool for semi automatic integration of heterogeneous sources schemata (relational, object and semi structured sources); it has been implemented within the MOMIS project and it carries out integration following a semantic approach which uses intelligent Description Logics-based techniques, clustering techniques and an extended ODMG-O...

the objects do not exist alone and are material. they were produced by men, which integrates the social systems. an object can be formed by other objects but also into a broader technical ensemble. technically, they are in relationship with other data such as materials, sources and forms of energy, other objects surrounding them. historians of technology believe that making the history of produ...

RNA editing in the mitochondria of kinetoplastid protozoa describes the insertion and (or) deletion of precise numbers of uridines at precise locations in the transcribed RNA. Such genes are known as cryptogenes. We describe dynamic programming algorithms to search for unknown cryptogenes and for the sequences that template the editing, gRNAs. Results of applying the cryptogenegRNA algorithm to...