BACKGROUND Depot medroxyprogesterone acetate is the most studied injectable contraceptive and also one of the most effective methods of contraception currently available. It is reversible, its use is independent of intercourse, and can be provided by trained non-medical staff making it particularly suitable for use in developing countries. The aim of this study is to determine the socio-demogra...

To the Editor:—I enjoyed the article by Dr. Stephen Abram. I would like to point out that an additional dimension to the discussion of effectiveness of epidural steroids can be found by applying the “numbers needed to treat” approach, as outlined in the excellent resource regarding the topic of pain relief using an evidence-based medicine approach published recently by McQuay and Moore. An addi...

1. Ovariectomy-delayed blastocysts flushed from mice treated with medroxyprogesterone acetate were injected into the lumina of immature mouse uterine horns. The horns were then maintained as organ cultures for 1-3 days in media that contained either (a) ethanol or ethanol plus (6) progesterone, (c) oestradiol or (d) progesterone and oestradiol. 2. Trophoblast invasion of the uterine stroma occu...

In the last two decades the prevailing opinion, supported by the "estrogen augmented by progesterone" hypothesis, has been that progesterone contributes to the development of breast cancer (BC). Support for this opinion was provided by the finding that some synthetic progestins, when added to estrogen in hormone replacement therapy (HRT) for menopausal complaints, increase the BC risk more than...

different contraceptive methods are used by breastfeeding mothers. to investigate the effects of progestogen - only contraceptives on human milk components, a non-randomized, follow-up study was carried out in iran (varamin) on 140 breastfeeding women, 51 of whom used progestogenonly contraception including progestogen-only pills (pop) or depo-medroxyprogesterone acetate (dmpa), and 89 used non...

BACKGROUND Sexual affairs are one of the physiological needs affecting human health. Sexual functioning disorders can reduce individual's capabilities and creativities. Sexual relations are in the center of women's quality of life. The most important family planning is to prevent unintended pregnancies. Injectable contraceptives protect women exposed to many complications and mortality due to u...

To clarify effect of postbreeding intramuscular administration of deslorelin on mares, plasma LH and progesterone concentrations and conception rate were evaluated. In Experiment 1, deslorelin, buserelin, or a placebo was administered on day 9 (day 0=day of last breeding or AI). Plasma samples were collected daily from days 6 to 15, and additional samples were taken after treatment. There was a...