cemchemotherapy (22, 27, 28), the recent work of Tnouet et a!. (5, 24, 25) using a daunomycmn-DNA compex activated by DNase is an important example. In particular, the novelty of this approach is not in the ar@zymaticrelease mechanism but in the endocytosis mechanism proposed by DeDuve et a!. (6). The high endocytotic activity, characteristic of many tu mom cells, allows the transport of the ma...