In 1972, I started my postgraduate studies in the lab of J.-L tin, at the National Taiwan Universit,~Taipei. The research project assigned to me was the synthesis of an analog of dansyl chloride (din%ethylaminonaphthalene sulfonyl chloride), which was both fluorescent and colored. Dansyl chloride was then a widely used fluorescent reagent for N-terminal analysis of proteins.’ To start the proje...

Perfumes (fragrance substances) are used in the formulation of consumer products to provide pleasure to the user and/or to mask malodours of some other ingredients in the products. Perfumes are also used in aromatherapy. A typical perfume may be composed of 10}300 substances selected from a battery of over 3000 synthetic and natural fragrance materials. It has been shown that approximately 2% o...

Abelmoschus moschatus Medik. is an aromatic and medicinal plant in the Malvaceae family, which is native to India. It is an erect hispid herbaceous trailing herb that grows up to 1.5m tall with a long slender tap root. Leaves are alternate, rough, hairy and heart-shaped. They have 3 to 5 lobes and can grow to 15cm long. Flowers resemble those of the hibiscus and are usually watermelon pink, alt...

Triclosan, the antimicrobial agent marketed for its germ-fighting capability in personal care products, is coming under close scrutiny. In April 2010 the U.S. Food and Drug Administration (FDA) announced it is conducting a scientific and regulatory review of triclosan in FDAregulated products, with publication of results expected in spring 2011. The agency also is collaborating with the U.S. En...

Triclosan, the antimicrobial agent marketed for its germ-fighting capability in personal care products, is coming under close scrutiny. In April 2010 the U.S. Food and Drug Administration (FDA) announced it is conducting a scientific and regulatory review of triclosan in FDAregulated products, with publication of results expected in spring 2011. The agency also is collaborating with the U.S. En...

For many years chemical risk assessments focused on exposures to single agents, but researchers are now paying more attention to chemical mixtures. Of particular interest are mixtures that people encounter in daily life, including combinations of ingredients in shampoo, deodorant, toothpaste, and other personal care products. In this issue of EHP, researchers describe a new informatics approach...

W a decade ago thoughts of metals and Alzheimer’s disease (AD) conjured up thoughts of tossing out your aluminum cookware, more recently, zinc, copper, and iron have been implicated in AD pathology. These metals are not derived from your saucepan or deodorant, but are already resident in the brain. Zinc is not a trace metal in the brain. In fact, zinc, copper, and iron concentrations in gray ma...

Triclosan, the antimicrobial agent marketed for its germ-fighting capability in personal care products, is coming under close scrutiny. In April 2010 the U.S. Food and Drug Administration (FDA) announced it is conducting a scientific and regulatory review of triclosan in FDAregulated products, with publication of results expected in spring 2011. The agency also is collaborating with the U.S. En...

Triclosan, the antimicrobial agent marketed for its germ-fighting capability in personal care products, is coming under close scrutiny. In April 2010 the U.S. Food and Drug Administration (FDA) announced it is conducting a scientific and regulatory review of triclosan in FDAregulated products, with publication of results expected in spring 2011. The agency also is collaborating with the U.S. En...

To the Editor: Although pathogenesis of allergic contact dermatitis (ACD) has been classically thought to be driven predominantly by Th1, its complex pathophysiology is now accepted include Th2, Th17, and Th22 pathways.1Dhingra N. Shemer A. Da Rosa J.C. et al.Molecular profiling skin identifies allergen-dependent differences in immune response.J Allergy Clin Immunol. 2014; 134: 362-372Abstract ...