Dengue is an acute mosquito-borne infection caused by dengue viruses from the genus flavivirus. Although viral myositis is common, myositis caused by dengue virus is not commonly reported. We present a case of an 18 year old female with serologically confirmed dengue fever presenting with severe myalgia and lower limb weakness. Twenty fold elevation of serum creatinine kinase level was noted. S...

Dengue, an arboviral infection transmitted by Aedes aegypti and Aedes albopictus mosquitoes, has emerged as one of the most important mosquito-borne viral disease. It is a global public health problem causing 50 to 390 million annual infections ranging from dengue fever, dengue hemorrhagic fever (DHF), to dengue shock syndrome (DSS). Climatic change, spread of dengue vectors to new geographic l...

Dengue virus infection is one of the most important human arboviral infection (World Health Organization). The worldwide incidence of dengue fever (DF), dengue haemorrhagic fever (DHF) and Dengue shock syndrome (DSS) has increased dramatically in recent decades (Geneva (2005) WHO report). Globally, it has been estimated that atleast 2.5 billion people are at risk of Dengue, and approximately 97...

he disease dengue fever (DF; also known as break-bone fever, dandy fever, and by other names) can be caused by any of 4 viruses within the virus family Flaviviridae, genus Flavivirus, i.e., dengue virus types 1–4 (DENV-1–4). Dengue fever is a short-duration , nonfatal illness characterized by sudden onset of headache, retroorbital pain, and high fever, joint pain, and rash. Whereas uncomplicate...

RV144 was a community-based HIV vaccine efficacy trial conducted in HIV-uninfected adults in Thailand, where dengue virus continues to cause a large number of infections every year. We attempted to document the accuracy of clinically diagnosed dengue episodes reported as serious adverse events (SAEs) and adverse events (AEs) and examine whether dengue serology would support the clinical diagnos...

We collected acute-phase serum samples from febrile patients at 2 major hospitals in Dhaka, Bangladesh, during an outbreak of dengue fever in 2001. A total of 18% of dengue-negative patients tested positive for leptospirosis. The case-fatality rate among leptospirosis patients (5%) was higher than among dengue fever patients (1.2%).

We reviewed case records of 40 in-patients (22 boys) with serologically confirmed dengue fever between 1st October and 30th November, 2013. Severe dengue was seen in 30, out of which 12 (30%) had compensated shock. Splenomegaly (6,15%) and encephalopathy (4,10%) were the commonest atypical features. Atypical manifestations of dengue fever were more common than that reported in the past.

The dengue viruses are estimated to cause several hundred thousand cases of dengue fever, dengue haemorrhagic fever and dengue shock syndrome annually. Attempts to prevent the infection focus on the development of a vaccine that would protect against all four serotypes of the dengue virus. Various biotechnological approaches are being explored, including the use of live attenuated or inactivate...