Dengue is the most important mosquito-borne viral disease. With four different serotypes, it is a burden throughout tropical and subtropical regions and a potential threat to almost half of the world’s population. Recent studies estimate that 50–100 million people are infected each year, of whom about 500,000 develop dengue haemorrhagic fever – a severe form of the disease – and 22,000 of whom ...

Dengue virus remains the most important arbovirus worldwide, and dengue disease poses a significant public health threat. Infection by one dengue serotype does not produce life-long protection against the other three serotypes, and severe disease may be due to non/poorly-neutralizing antibodies to heterologous or homologous dengue serotypes. As such, development, validation, and implementation ...

Dengue hemorrhagic fever cases in Bali have increased the past decade. Control and eradication efforts must be optimized. In order to create dengue-free zones, accurate information a comprehensive strategy for accelerating dengue vector management are required. This paper is based on empirical, field, epidemiological studies program evaluations guided by health belief model approach. this regar...

Two major epidemic waves of dengue 1 occurred in Rio de Janeiro, Brazil, in 1986 and 1987. This article reports the results of a survey of Rio schoolchildren who were tested serologically for antibodies to dengue 1 before and after the second major epidemic wave. The highest percentages of positive subjects were found in districts with relatively poor socioeconomic conditions and mosquito contr...

BACKGROUND No vaccine is currently available for dengue virus (DENV), therefore control programmes usually focus on managing mosquito vector populations. Entomological surveys provide the most common means of characterising vector populations and predicting the risk of local dengue virus transmission. Despite Indonesia being a country strongly affected by DENV, only limited information is avail...

INTRODUCTION Dengue is a rapidly expanding global health problem. Approximately 2.5 billion people live in dengue-risk regions with about 100 million new cases each year worldwide. The cumulative dengue diseases burden has attained an unprecedented proportion in recent times with sharp increase in the size of human population at risk. The management of dengue virus infection is essentially supp...

Deltamethrin-resistant Aedes aegypti currently threatens the effectiveness of dengue hemorrhagic fever control operations in Thailand. Although a previous study has suggested that insecticide resistance may increase Ae. aegypti susceptibility to dengue-2 virus infection, our experimental data showed no significant association between laboratory-induced deltamethrin-resistance in a Thai Ae. aegy...

Human immunodeficiency virus (HIV) load is suppressed during dengue virus infection. The NS5A phosphoprotein of GB virus C (a related flavivirus) inhibits HIV replication in vitro. To determine whether the dengue virus NS5 protein inhibits HIV replication, CD4(+) T cell lines expressing this protein were generated. HIV replication in dengue virus NS5-expressing cells decreased by >90% compared ...

Dengue infection, one of the most devastating mosquito-borne viral diseases in humans, is now a significant problem in several tropical countries. The disease, caused by the four dengue virus serotypes, ranges from asymptomatic infection to undifferentiated fever, dengue fever (DF), and severe dengue hemorrhagic fever (DHF) with or without shock. DHF is characterized by fever, bleeding diathesi...