Extracellular and intracellular cues affect neuronal morphology and contribute to brain diseases, such as schizophrenia, and injury. First, we examined how extracellular cues influence branching parameters of hippocampal neurons. Brain injury or disease can initiate changes in local or global stiffness of brain tissue. While stiffness of the extracellular environment is known to affect the morp...

Let D be a dendrite and f : D → D a continuous map. Denote by E(D) and B(D) the sets of endpoints and branch points of D respectively. We show that if E(D) is countable (resp. B(D) is discrete) then f is pointwise-recurrent if and only if f is pointwise periodic homeomorphism (resp. every point in D\E(D) is periodic).

Neuronal morphology plays a significant role in determining how neurons function and communicate. Specifically, it affects the ability of neurons to receive inputs from other cells and contributes to the propagation of action potentials. The morphology of the neurites also affects how information is processed. The diversity of dendrite morphologies facilitate local and long range signaling and ...

Microcircuits composed of dendrite-targeting inhibitory interneurons and pyramidal cells (PCs) are fundamental elements of cortical networks, however, the impact of individual interneurons on pyramidal dendrites is unclear. Here, we combine paired recordings and calcium imaging to determine the spatial domain over which single dendrite-targeting interneurons influence PCs in olfactory cortex. W...