A variety of pathologic variants of cutaneous squamous cell carcinoma (SCC) has been reported, and the signet-ring variant of cutaneous SCC is extremely uncommon. We reported an 83-year-old man with signet-ring SCC arising on the back of the finger. As far as we know, only 4 cases have been described in detail, and one dermatopathologic report focused on the presence of signet-ring cells briefl...

[1] We have examined residual magnetic field vectors observed in Saturn’s magnetosphere during the first 2 years of the Cassini mission and have fit them to a simple axisymmetric model of the ring current in the middle magnetosphere. We then examine the variations of the ring current parameters with size of the magnetosphere. In addition, we obtain secondary parameters, including the value of t...

2014 After some numerical experience, we developed a technique allowing the fast computation of an integral appearing in the mathematical study of the diffraction rings produced by the self phase modulation of a Gaussian laser beam through a non linear thin film. The results obtained by means of a simple microcomputer (IBM-PC) are shown to may be used for the deduction of the non linearity prop...

this paper consider the   general  forms of $(alpha,beta)$-fuzzyleft ideals (right ideals, bi-ideals, interior ideals) of an orderedsemigroup, where$alpha,betain{in_{gamma},q_{delta},in_{gamma}wedgeq_{delta}, in_{gamma}vee q_{delta}}$ and $alphaneqin_{gamma}wedge q_{delta}$. special attention is paid to$(in_{gamma},ivq)$-left ideals (right ideals, bi-ideals, interiorideals) and some related  pr...

Abstract Fix an odd prime $p$. The results in this paper are modeled after work of Hesselholt and Hesselholt–Madsen on the $p$-typical absolute de Rham–Witt complex mixed characteristic. We have two primary results. 1st result is exact sequence that describes kernel restriction map over $A$, where $A$ ring integers algebraic extension $\textbf{Q}_p$ or a $p$-torsion-free perfectoid ring. 2nd de...

Tetrahydrocannabinol (Delta(9)-THC), the primary psychoactive ingredient in marijuana, is subject to cytochrome P450 oxidation and subsequent UDP-glucuronosyltransferase (UGT)-dependent glucuronidation. Many studies have shown that CYP2C9 and CYP3A4 are the primary enzymes responsible for these cytochrome P450-dependent oxidations, but little work has been done to characterize phase II metaboli...

The comparative biological activity of 21 naturally occurring or synthetically derived steroids, 7 tetracyclic and pentacylic triterpenoids, and antheridiol incubated with cultures of Phytophthora cactorum has been examined. There was greater dependence on precise steric features of the sterol side chain than on the extent of nuclear unsaturation in inducing oospore formation. There was no sign...

The solution conformation of the homogeneous, heparin-derived tetrasaccharide delta UA2S(1-->4)-alpha-D-GlcNpS6S(1-->4)-alpha-L-IdoAp2S (1-->4)-alpha-D-GlcNpS6S (residues A, B, C and D respectively, where IdoA is iduronic acid) has been investigated by using 1H- and 13C-NMR. Ring conformations have been defined by J-coupling constants and inter-proton nuclear Overhauser effects (NOEs), and the ...

Salvinorin A (1), from the sage Salvia divinorum, is a potent and selective kappa opioid receptor (KOR) agonist. We screened other salvinorins and derivatives for binding affinity and functional activity at opioid receptors. Our results suggest that the methyl ester and furan ring are required for activity but that the lactone and ketone functionalities are not. Other salvinorins showed negligi...