Acentric and atelomeric double minute chromatin found in human cancer cells are eliminated from cells by selective incorporation into the micronuclei. We showed previously that most of the micronuclei were formed at S phase and mediated by the nuclear bud-shaped structures that selectively entrap double minutes. In this paper, we have examined the behavior of double minutes in relation to the n...

A recessive ascospore mutant of Neurospora tetrasperma, named bud, was isolated from a wild-collected heterokaryotic strain with four different nuclear components. bud segregates as a single mendelian gene. When bud is homozygous, meiosis is apparently normal but postmeiotic events are not. Abnormal orientation of spindles at the postmeiotic mitosis often results in failed pair-wise association...

to evaluate the effect of shoot girdling, fruit thinning, urea, sucrose and zinc on inflorescence bud retention in pistachio, an experiment comprised of 12 treatments including girdling, fruit thinning, application of urea (0.5%), and sucrose (3 and 5%) and their combination of the first two with urea plus zinc sulfate (0.05 and 0.1% of pure zinc) as well as a combination of the two with urea, ...

OBJECTIVE To compare the effectiveness of budesonide/formoterol using fixed dosing (BUD/FORM) with inhaled corticosteroid (ICS) alone or alternative ICS and long-acting beta(2)-agonist (LABA) regimens for adults with moderate/severe asthma. METHODS BIOSIS, CENTRAL, EMBASE and MEDLINE were searched for abstracts and papers. All searching was completed in July 2006. No restriction was placed on...

In three studies, we examined factors that may temporarily attenuate information search. People are generally curious and dislike uncertainty, which typically encourages them to look for relevant information. Despite these strong forces that promote information search, people sometimes deliberately delay obtaining valuable information. We find they may do so when they are concerned that the inf...

Asthma control is improved by combining inhaled corticosteroids with long-acting beta2-agonists. However, fluctuating asthma control still occurs. We hypothesized that in patients receiving low maintenance dose budesonide/formoterol (bud/form), replacing short-acting beta2-agonist (SABA) reliever with as-needed bud/form would provide rapid symptom relief and simultaneous adjustment in antiinfla...

A 14-yr-old girl with Down syndrome develimmune sera revealed that the inhibitor was oped a unique type of circulating inhibitor an immunoglobulin of lgG class with both causing a mild bleeding tendency and interand A determinants. Isolated inhibitor defering strongly with coagulation tests, includlayed the release of fibrinopeptide A from a ing reptilase time, and with the reaction of normal f...