INTRODUCTION Development of hypocalcaemia is a serious complication to total thyroidectomy (TT). The measurement of intact plasma parathyroid hormone (iPTH) has been internationally described as a good predictor of hypocalcaemia. Despite this, consensus in the field has yet to be reached among clinicians. We aimed to evaluate if measurement of iPTH 24 hours post-operatively (24-iPTH) can identi...

BACKGROUND Calcium disorders are common in both intensive care units and in patients with chronic kidney disease and are associated with increased morbidity and mortality. It is unknown whether calcium abnormalities in unselected emergency department admissions have an impact on in-hospital mortality. METHODS This cross-sectional analysis included all admissions to the Emergency Department at...

OBJECTIVE To investigate changes in the electrocardiographic QT interval during rapidly induced, sustained hypocalcaemia in healthy volunteers. DESIGN Serial rate corrected QT measurements were made during and after a variable rate trisodium citrate infusion designed to "clamp" the whole blood ionised calcium concentration 0.20 mmol/l below baseline for 120 min. SUBJECTS 12 healthy teetotal...

A patient of 29 years is described with Noonan's syndrome and idiopathic hypoparathyroidism, who presented with epilepsy and myoclonus. Correction of the hypocalcaemia resulted in improvement of his myoclonus and psychiatric abnormalities. The embryological significance of the association is discussed.

Cerebrospinal fluid absorption has been studied in a patient with primary hypoparathyroidism, papilloedema, and epilepsy. A marked reduction of cerebrospinal fluid transport into plasma was demonstrated which returned to normal after correction of the hypocalcaemia.

Abstract Introduction Postoperative surgical hypoparathyroidism (PoSH) following thyroid surgery is well known complication. Several predictive factors have been identified including perioperative parathyroid hormone (PTH) levels. The aim of the study to determine how a drop in compares postoperative day one PTH predicting hypocalcaemia. Methods Medical records consecutive patients who had eith...

Abstract Introduction Total parathyroidectomy on patients with hyperparathyroidism traditionally required an inpatient hospital stay to monitor for postoperative hypocalcaemia. Our centre developed a safe protocol in 2015 which enables total parathyroidectomies be carried out as day-case procedure. This protocol, conjunction the renal physicians, involves giving patient oral alfacalcidol preope...