نتایج جستجو برای: default mode network dmn

تعداد نتایج: 892432  

Journal: :Neuroscience letters 2011
Christine Wiebking Moritz de Greck Niall W Duncan Alexander Heinzel Claus Tempelmann Georg Northoff

Imaging studies investigating the default-mode network (DMN) of the brain revealed the phenomenon of elevated neural responses during periods of rest. This effect has been shown to be abnormally elevated in regions of the DMN concerning mood disorders like major depressive disorder (MDD). Since these disorders are accompanied by impaired emotional functioning, this leads to the suggestion of an...

2016
Srikanth Ryali Kaustubh Supekar Tianwen Chen John Kochalka Tom Weidong Cai Jonathan Nicholas Aarthi Padmanabhan Vinod Menon

Little is currently known about dynamic brain networks involved in high-level cognition and their ontological basis. Here we develop a novel Variational Bayesian Hidden Markov Model (VB-HMM) to investigate dynamic temporal properties of interactions between salience (SN), default mode (DMN), and central executive (CEN) networks-three brain systems that play a critical role in human cognition. I...

2015
Mahiko Konishi Donald George McLaren Haakon Engen Jonathan Smallwood Satoru Hayasaka

Although many different accounts of the functions of the default mode network (DMN) have been proposed, few can adequately account for the spectrum of different cognitive functions that utilize this network. The current study used functional magnetic resonance imaging (fMRI) to explore the hypothesis that the role of the DMN in higher order cognition is to allow cognition to be shaped by inform...

2015
Wenbin Guo Feng Liu Jianrong Liu Miaoyu Yu Zhikun Zhang Guiying Liu Changqing Xiao Jingping Zhao Vedat Sar.

The default-mode network (DMN) has been implicated in the neurobiology of major depressive disorder (MDD), and the cerebellum is suggested to be involved in high-order cognitive network such as the DMN. However, the specific contribution of the cerebellum to the DMN alterations remains equivocal. This study was conducted to examine the cerebellar-DMN connectivity in drug-naive MDD directly by u...

2017
Peter McColgan Adeel Razi Sarah Gregory Kiran K. Seunarine Alexandra Durr Raymund A.C. Roos Blair R. Leavitt Rachael I. Scahill Chris A. Clark Doug R. Langbehn Geraint Rees Sarah J. Tabrizi

Depression is common in premanifest Huntington's disease (preHD) and results in significant morbidity. We sought to examine how variations in structural and functional brain networks relate to depressive symptoms in premanifest HD and healthy controls. Brain networks were constructed using diffusion tractography (70 preHD and 81 controls) and resting state fMRI (92 preHD and 94 controls) data. ...

2014
Xingchao Wang Yang Fan Fu Zhao Zhenmin Wang Jianqiao Ge Kai Zhang Zhixian Gao Jia-Hong Gao Yihong Yang Jin Fan Qihong Zou Pinan Liu

The deprivation of sensory input after hearing damage results in functional reorganization of the brain including cross-modal plasticity in the sensory cortex and changes in cognitive processing. However, it remains unclear whether partial deprivation from unilateral auditory loss (UHL) would similarly affect the neural circuitry of cognitive processes in addition to the functional organization...

Journal: :Pain 2013
Marco L Loggia Jieun Kim Randy L Gollub Mark G Vangel Irving Kirsch Jian Kong Ajay D Wasan Vitaly Napadow

Neuroimaging studies have suggested the presence of alterations in the anatomo-functional properties of the brain of patients with chronic pain. However, investigation of the brain circuitry supporting the perception of clinical pain presents significant challenges, particularly when using traditional neuroimaging approaches. While potential neuroimaging markers for clinical pain have included ...

Journal: :Forschende Komplementarmedizin 2012
Alexander Otti Michael Noll-Hussong

As a complementary medical procedure, acupuncture has a significant impact on the treatment of acute and chronic pain. Though the physiological mechanisms behind this method are still unclear, acupuncture has been claimed to rely also on changes in the central nervous system. Recent functional imaging studies indicate that the so-called default mode network (DMN) which consists of cortical midl...

Journal: :Neurology 2013
Jasmeer P Chhatwal Aaron P Schultz Keith Johnson Tammie L S Benzinger Clifford Jack Beau M Ances Caroline A Sullivan Stephen P Salloway John M Ringman Robert A Koeppe Daniel S Marcus Paul Thompson Andrew J Saykin Stephen Correia Peter R Schofield Christopher C Rowe Nick C Fox Adam M Brickman Richard Mayeux Eric McDade Randall Bateman Anne M Fagan Allison M Goate Chengjie Xiong Virginia D Buckles John C Morris Reisa A Sperling

OBJECTIVE To investigate default mode network (DMN) functional connectivity MRI (fcMRI) in a large cross-sectional cohort of subjects from families harboring pathogenic presenilin-1 (PSEN1), presenilin-2 (PSEN2), and amyloid precursor protein (APP) mutations participating in the Dominantly Inherited Alzheimer Network. METHODS Eighty-three mutation carriers and 37 asymptomatic noncarriers from...

2016
Yingying Yin Xiaofu He Mingze Xu Zhenghua Hou Xiaopeng Song Yuxiu Sui Zhi Liu Wenhao Jiang Yingying Yue Yuqun Zhang Yijun Liu Yonggui Yuan

To identify the association between the functional and structural changes of default mode network (DMN) underlying the cognitive impairment in Late-onset depression (LOD), 32 LOD patients and 39 normal controls were recruited and underwent resting-state fMRI, DTI scans, and cognitive assessments. Seed-based correlation analysis was conducted to explore the functional connectivity (FC) of the DM...

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