DESCRIPTION The American College of Physicians (ACP) developed this guideline to present the evidence and provide clinical recommendations on prophylaxis of venous thromboembolism for hospitalized nonsurgical patients (medical patients and patients with acute stroke). METHODS This guideline is based on published literature on the topic from 1950 through April 2011 that was identified by using...

Guidelines recommend thromboprophylaxis for at least 10 days to prevent venous thromboembolism in patients undergoing high-risk orthopedic surgery, such as total hip arthroplasty (THA) or total knee arthroplasty (TKA). Furthermore, the recently updated ACCP guidelines also recommend extending the duration of thromboprophylaxis for 28 to 35 days following THA or hip fracture surgery as the risk ...

A retrospective study of Scottish hospital inpatients aged 15 years or less has revealed, over a 4-year period, 36 cases of venous thrombosis or phlebitis. Of these 10 were considered to have deep venous thrombosis; 2 cases were associated with obvious pulmonary embolism and 2 cases developed chronic venous insufficiency. change in the coding allocations are proposed. There are "high risk" situ...

A patient with a circulating lupus anticoagulant in the absence of systemic lupus erythematosus developed recurrent deep venous thromboses and pulmonary emboli. Pulmonary emboli recurred despite prolonged oral anticoagulant therapy and resulted in fatal pulmonary arterial hypertension. Extended anticoagulant therapy alone may not prevent recurrent thromboembolism in patients with a lupus antico...

The annual incidence of venous thromboembolism is approximately 0.1 percent; the rate increases from 0.01 percent among persons in early adulthood to nearly 1 percent among those who are at least 60 years old. 1,2 More than half of these events involve deep-vein thrombosis. To minimize the risk of fatal pulmonary embolism, accurate diagnosis and prompt therapy are crucial. 3 Long-term complicat...

The introduction of venography into patient care was a major advance because it was the first accurate method for the diagnosis of DVT. Compression ultrasound has since become the preferred test for patients with suspected DVT because, unlike venography, it is simple, non-invasive and widely available. Venography has facilitated the development and approval of new anticoagulants and remains wid...

venous thromboembolism: an evaluation of the use of thromboprophylaxis guidelines. Chest 2001; 120: 1964–71. 6 Alikhan R,Wilmott R, Agrawal S. Use of thromboprophylaxis in nonsurgical patients: survey of a London teaching hospital. Blood 2001; 98: 1142 (abstract). 7 Ageno W, Squizzato A, Ambrosini F, Dentali F, Marchesi C, Mera V, Steidl L, Venco A. Thrombosis prophylaxis in medical patients: a...

BACKGROUND Individual risk of recurrent venous thromboembolism affects patient management and might differ between men and women. We did a meta-analysis to assess from available evidence whether men and women have the same risk of recurrent venous thromboembolism after stopping anticoagulant treatment. METHODS Eligible articles were identified by searches of MEDLINE (source PubMed, 1966 to Fe...

BACKGROUND The prevention of venous thromboembolism has been identified as a leading priority in hospital safety. Recommended parenteral anticoagulant agents with different indications for the prevention and treatment of venous thromboembolism include unfractionated heparin, low-molecular-weight heparins and fondaparinux. Prescribing decisions in venous thromboembolism management may seem compl...

OBJECTIVE To determine whether antipsychotic drugs are associated with an increased risk of venous thromboembolism, and to examine risks by type of antipsychotic, potency, and dose. DESIGN Population based nested case-control study. SETTING The UK QResearch primary care database. PARTICIPANTS Patients (cases) with a first ever record of venous thromboembolism between 1 January 1996 and 1 ...