OBJECTIVES To evaluate the effectiveness of deep anterior lamellar keratoplasty (DALK) using Melles technique (technique B) in patients with advanced keratoconus versus a classic technique, penetrating keratoplasty (technique A). METHODOLOGY Retrospective descriptive comparative study between technique A and technique B in homogeneous groups. RESULTS Best corrected visual acuity (Snellen te...

PURPOSE To evaluate difference in therapeutic outcomes between deep anterior lamellar keratoplasty (DALK) and penetrating keratoplasty (PKP) for the clinical treatment of keratoconus. METHODS A comprehensive search was conducted in Pubmed, EMBASE, Cochrane Library, and Web of science. Eligible studies should include at least one of the following factors: best corrected visual acuity (BCVA), p...

Purpose: To compare clinical outcomes following penetrating keratoplasty (PK) versus deep anterior lamellar keratoplasty (DALK) for keratoconic patients with vernal keratoconjunctivitis (VKC). Methods: In this retrospective comparative study, the records of 69 keratoconic eyes with VKC that underwent PK (n=43, group 1) or DALK (n=26, group 2) were compiled. Postoperative best-corrected visual a...

OBJECTIVE To compare outcomes between penetrating keratoplasty (PK) and deep anterior lamellar keratoplasty (DALK) in patients with keratoconus. DESIGN Retrospective cohort study. METHODS Data of 90 DALK and 49 procedures from conversion to PK, performed by a single surgeon (R.D.) from 2006 to 2011 were analysed. Outcomes on corrected distance visual acuity (BCVA), astigmatism, time to firs...

The aim of this study was to construct a rabbit anterior corneal replacement for transplantation using acellular porcine corneal matrix (APCM) and rabbit epithelial or stromal cells. APCM was prepared from fresh porcine cornea treated with 0.5% (wt./vol.) sodium dodecyl sulfate (SDS) solution. The expanded stromal cells were first injected into APCM parallel to its surface and were cultured in ...

lar to the earlier described case, suggesting an invasive postoperative ingrowth process. The X-Y karyotyping revealed that the epithelial cells were of donor origin. The technique of posterior lamellar keratoplasty is relatively new and technically difficult, with a surgeon’s learning curve. The most critical step is the preparation of the posterior lamellar disc by hand or by use of a microke...

BACKGROUND To compare outcomes of femtosecond laser-assisted deep anterior lamellar keratoplasty (FSL-DALK) and penetrating keratoplasty (FSL-PK) for the treatment of keratoconus. METHODS Twenty eight eyes underwent FSL-DALK (consisted of 12 eyes in the FSL-DALKa subgroup without baring the Descemet's membrane and 16 eyes in the FSL-DALKb subgroup baring the Descemet's membrane using big-bubb...

BACKGROUND This study describes the in vivo confocal microscopy findings in two patients who had deep anterior lamellar keratoplasty (DALK) following Descemet's stripping automated endothelial keratoplasty (DSAEK). METHODS The study reviewed the cases of two patients who first underwent DSAEK followed by DALK when their vision failed to improve due to residual stromal scarring. In the first c...

BACKGROUND Indications for corneal transplantation in developed and developing nations differ according to the different spectrum of corneal disease in each country. OBJECTIVE The purpose of this study is to analyze the changing indications and surgical techniques for corneal transplantation over the past 20 years at a tertiary referral center in Turkey. METHODS We retrospectively reviewed ...

Corneal transplantation or keratoplasty has developed rapidly in the past 10 years. Penetrating keratoplasty, a procedure consisting of full-thickness replacement of the cornea, has been the dominant procedure for more than half a century, and successfully caters to most causes of corneal blindness. The adoption by specialist surgeons of newer forms of lamellar transplantation surgery, which se...