2 Group Sequential Designs (GSD) 2 2.1 GST object . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3 2.1.1 Alpha spending function (SF) . . . . . . . . . . . . . . . . 4 2.2 plan.GST example . . . . . . . . . . . . . . . . . . . . . . . . . . 4 2.3 Overall p-values for GSDs . . . . . . . . . . . . . . . . . . . . . . 6 2.3.1 Repeated p-values in a classical GSD . . . . . . . . . . . ...

©AsiaPacific MediaEducator Issue No.11 July Dec. 2001 T essay examines the debate surrounding the potential impact of new technologies on traditional newspapers in the 21st Century. Using the Internet as an example, the essay compares the situation in developing African countries with the western world. Specifically the essay examines the various ways the Internet technology has impacted news c...

1 From the Dept of Radiology, Vanderbilt Univ Medical Ctr, RR-1223, MCN, 1161 21st Ave South, Nashville, TN 37232-2675 (C.L.P.); Dept of Radiology, Univ of Michigan Health Systems, Ann Arbor (H.P.C.); Dept of Radiology, Univ of Texas M.D. Anderson Cancer Ctr, Houston (J.G.G.); Dept of Radiology, Univ of Chicago, Ill (M.L.G.); Dept of Radiology, Duke Univ Medical Ctr, Durham, NC (J.A.I.); Dept o...

OBJECTIVE To determine the frequency of dyslipidemia in patients with lupus nephritis and its association with the degree of proteinuria. METHODS This cross-sectional analytic study included 65 patients who fulfilled the ACR (American College of Rheumatology) criteria for SLE and had renal involvement, presenting to the Division of Rheumatology, Fatima Memorial Hospital (FMH), and Lahore from...