Background—Endothelial dysfunction plays an important role in the early development of atherosclerosis and vascular complications in type 2 diabetes mellitus. Increased expression and activity of arginase, metabolizing the nitric oxide substrate L-arginine, may result in reduced production of nitric oxide and thereby endothelial dysfunction. We hypothesized that inhibition of arginase activity ...

Background: Objectives of current study were to find out the proportion types diabetes and know factors for adverse maternal fetal outcome in pre-gestational gestational at a tertiary care Institute compare outcomes between GDM.Methods: Prospective descriptive conducted department obstetrics gynaecology, center over period 1 year. The inclusion criteria were: (pregnant women with type & 2 m...

type 1 diabetes mellitus is frequently associated with autoimmune thyroid disease (atd).genetic susceptibility for autoantibody formation in association with atd and type 1 diabetes mellitus has been described with varying frequencies, but there is still debate about its prevailing situation in iran.  we have therefore investigated the prevalence of anti-thyroid peroxidase (anti-tpo) and anti t...

Metformin is an antihyperglycemic agent commonly used for the treatment of Type II diabetes mellitus. However, its effects on patients are derived usually from clinical experiments. In this study, a dynamic model of Type II diabetes mellitus with the treatment of metformin is proposed. The Type II diabetic model is a modification of an existing compartmental diabetic model. The dynamic simulati...

Background: Diabetes mellitus is the most prevailing non- communicable diseases worldwide. It main reason of morbidity and mortality. Cognitive dysfunction one major complications associated with diabetes. a risk factor for cognitive decline as duration diabetes progress if accompanied by hypoglycemic attacks. Aim: To determine frequency dementia in patients suffering from type II mellitus. Stu...

objective: to identify the proportion and some selected characteristics of juvenile diabetics attending birdem hospital. materials and methods: this was a cross sectional study. the study was conducted in the birdem hospital. all diabetic young aged up to 18 years who visit birdem hospital were included in study population. the sample size was 240. results: it was observed that among the respon...

Cardiovascular autonomic dysfunction is a common complication of the patients with type 2 diabetes mellitus (T2DM) [1-5], which is associated with a higher risk of sudden cardiac death in T2DM patients [1,4,6]. Unlike type 1 diabetes mellitus, the mechanisms responsible for the cardiovascular autonomic dysfunction have not been explored in T2DM even though T2DM affects 90 to 95% of the diabetic...