Introduction: Assessment of myocardial perfusion by dynamic contrast enhanced MRI (DCE-MRI) is still an evolving technique and is yet to become a part of standard diagnostic assessment of patients with coronary heart disease (CHD). Despite its advantages over other tomographic methods, the transition of DCE-MRI from a promising research technique into a robust clinical tool has been impeded by ...

Following the primary traumatic injury, spinal cord tissue undergoes a series of pathobiological changes, including compromised blood-spinal cord-barrier (BSCB) integrity. These vascular changes occur over both time and space. In an experimental model of spinal cord injury (SCI), longitudinal dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI)studies were performed up to 56 days post...

BACKGROUND To determine the feature values of head and neck paragangliomas on diffusion-weighted imaging (DWI) and dynamic contrast enhanced (DCE) magnetic resonance imaging (MRI). METHODS Patients with primary head and neck paraganglioma who underwent both DWI and DCE-MRI before treatment between January 2010 and June 2013 were identified. Two radiologists assessed apparent diffusion coeffic...

INTRODUCTION Synovial inflammation and joint destruction in rheumatoid arthritis (RA) may progress despite clinical remission. Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) is increasingly used to detect synovial inflammation in RA. Although small joints such as metacarpophalangeal (MCP) joints are mainly affected by RA, MRI findings have never been directly compared to histolo...

Molecular magnetic resonance imaging targeted to an endothelial integrin involved in neoangiogenesis was compared to DCE-US and immunochemistry to assess the early response of three different therapeutic agents in renal cell carcinoma. Human A498 renal cells carcinoma was subcutaneously inoculated into 24 nude mice. Mice received either phosphate-buffered saline solution, sunitinib, everolimus,...

Immune checkpoint inhibitors (ICIs) targeting programmed death ligand?1 (PD?L1) are highly promising therapies for oral squamous cell carcinoma (OSCC). The assessment of PD?L1 expression may help predicting the therapeutic effect ICIs and, thus, benefit patient selection. Contrast index (CI) parameters derived from dynamic contrast?enhanced magnetic resonance imaging (DCE?MRI) have been proven ...

AIMS To carry out a meta-analysis to assess the effectiveness of magnetic resonance imaging (MRI) during the follow-up of patients with prostate cancer after undergoing external beam radiotherapy (EBRT) or radical prostatectomy. MATERIALS AND METHODS MEDLINE, EMBASE and other databases were searched for relevant original articles published from January 1995 to October 2011. Methodological qua...

Introduction: K is commonly used as a biomarker of drug efficacy in tumors, but its interpretation is complex when using clinically available low molecular weight contrast agents. Dynamic CT (DCE-CT) potentially provides independent measures of perfusion and permeability. The goals of this study were (1) to compare the reproducibility (scan-rescan) of DCE-CT and DCE-MRI biomarkers, and (2) to c...

PURPOSE To evaluate the interobserver variability of gross tumor volume (GTV) - delineation of Dominant Intraprostatic Lesions (DIPL) in patients with prostate cancer using published MRI criteria for multiparametric MRI at 3 Tesla by 6 different observers. MATERIAL AND METHODS 90 GTV-datasets based on 15 multiparametric MRI sequences (T2w, diffusion weighted (DWI) and dynamic contrast enhance...

OBJECTIVE To assess the diagnostic value of dynamic contrast medium-enhanced magnetic resonance imaging (DCE-MRI) in detection of thyroid carcinoma compared with fine-needle aspiration biopsy and frozen section analysis in multinodular goiter. DESIGN Prospective clinical study. SETTING University hospital. PATIENTS Thirty consecutive patients with nodular goiter without any clinical risk ...