A surge of interest in data-intensive computing has led to a drastic increase the demand for data centers. Given this growing popularity, centers are becoming primary contributor increased consumption energy worldwide. To mitigate problem, paper revisits DVFS (Dynamic Voltage Frequency Scaling), well-known technique reduce usage processors, from viewpoint distributed systems. Distributed system...

Significance We report an intersubunit interaction within the coronavirus replication–transcription complex that is critical for replication and evolutionarily conserved. provide evidence nsp12-associated NiRAN domain has nucleoside monophosphate (NMP) transferase activity in trans identified nsp9, RNA-binding protein, as its target. catalyzes covalent attachment of NMP moiety to conserved nsp9...

In this paper, we present an efficient technique for optimising data replication under the data parallel programming model. We propose a precise mathematical representation for data replication which allows handling replication as an explicit, separate stage in the parallel data placement problem. This representation takes the form of an invertible mapping. We argue that this property is key to...

Background: Sodium valproate, an anticonvulsant drug, is reported to stimulate Human Immunodeficiency Virus type 1 and Human cytomegalovirus replication. Since epileptic patients undergoing sodium valproate therapy may suffer from various virus infections, the effect of this drug on replication of viruses especially those affecting neuronal tissues such as Herpes simplex virus type 1 is worthy ...

The Varicella-Zoster Virus (VZV) genome contains both cis-acting and trans-acting elements, which are important in viral DNA replication. The cis-acting elements consist of two copies of oriS, and the trans-acting elements are those genes whose products are required for virus DNA replication. It has been shown that each of the seven genes required for ori-dependent DNA synthesis of Herpes Simpl...