objective(s) single injection of naloxone, a selective antagonist of morphine, prior to the drug conditioning testing was used to investigate on morphine dependence. materials and methods conditioning to morphine (2.5-10 mg/kg, s.c.) was established in adult male wistar rats (weighing 200-250 g) using an unbiased procedure. nitric oxide agents were microinjected into the central amygdala prior ...

sludge drying bed is preferred to mechanical methods due to the need for very simple technology. due to restriction of natural dewatering, we tried to eliminate some of these limitations by the tests and studies of assumptions. in this study, the effect of hydrostatic suction and sludge chemical conditioning has been studied in the natural sludge dewatering optimization. at first, hydrostatic s...

Threat conditioning procedures have allowed the experimental investigation of the pathogenesis of Post-Traumatic Stress Disorder. The findings of these procedures have also provided stable foundations for the development of relevant intervention programs (e.g. exposure therapy). Statistical inference of threat conditioning procedures is commonly based on p-values and Null Hypothesis Significance ...

Converging evidence examining the effects of post-training manipulations of the hippocampus suggests that the hippocampus may play a time-limited role in the maintenance of a variety of forms of memory. In particular, either lesions or inactivation of the dorsal hippocampus results in many cases in a time-limited retrograde impairment in nondiscriminative contextual conditioning paradigms. Howe...

BACKGROUND AND OBJECTIVES We argue that the stimuli used in traditional fear conditioning paradigms are too simple to model the learning and unlearning of complex fear memories. We therefore developed and tested an adapted fear conditioning paradigm, specifically designed for the study of complex associative memories. Second, we explored whether manipulating the meaning and complexity of the CS...

Many socio-economic studies rely on panel data as they also provide detailed demographic information about consumers. For example, advertisers use TV and web metering panels to estimate ads effectiveness in selected target demographics. However, panels often record only a fraction of all events due to non-registered devices, technical problems, or work usage. Goerg et al. (4) present a beta-bin...

I show how to construct the likelihood function for the conditional maximum likelihood estimator in dynamic, unobserved effects models where not all conditioning variables are strictly exogenous. The method for handling the initial conditions problem appears to be novel, and offers a flexible, relatively simple alternative to existing methods.  2000 Elsevier Science S.A. All rights reserved.

A heat-conditioning treatment of 10 mm at 45°followed by 370 incubation resulted in maximal thermotolerance 8 hr later. The D@of the heat survival curve increased from 4.5 mm (control) to 19.8 mm at 45°.Two heat-conditioning treatments (10 mm at 45°+ 4 hr at 37°+ 15 mm at 45°)resulted in a higher thermotolerance maximum (D@= 26.7 mm) 8 hr after the second • conditioning treatment. In com...

A combination of hot water (a rinse at 62 degrees C for 20 s) and conditioning (pre-storage at 16 degrees C for 7 d) treatments synergistically reduced chilling injury development in grapefruit (Citrus paradisi, cv. "Star Ruby") during cold storage at 2 degrees C, suggesting that the treatments may activate different chilling tolerance responses. To study the molecular mechanisms involved, chil...

Previously, we proposed a two-stage model for an in vitro neural correlate of eyeblink classical conditioning involving the initial synaptic incorporation of glutamate receptor A1 (GluA1)-containing α-amino-3-hydroxy-5-methylisoxazole-4-propionic acid type receptors (AMPARs) followed by delivery of GluA4-containing AMPARs that support acquisition of conditioned responses. To test specific eleme...