OBJECTIVES To describe a nationwide system for postmarketing follow up of new antirheumatic drugs in Sweden, and to analyse safety and effectiveness in an etanercept treated patient cohort. METHODS Etanercept became available in Sweden for prescribing on a named patient basis in 1999. All patients treated were included in a follow up of intensified adverse event reporting and recording of cli...

Background: RA is an autoimmune disease that presented with chronic inflammation due to synovial hyperplasia, this disease progress through joint destruction. DMARD s is the most usual drug for treating this disease that accompanies with various adverse effects and complications. Aim of this study is to evaluate anti-inflammatory effect of a compound herbaceous drug consist of (ginger, Curcumin...

The aim of the study was to examine lipid profiles, arterial stiffness (AS), carotid intima-media thickness (cIMT), in 55 women with RA without overt cardiovascular disease (СVD) treated with rituximab (RTX).The following parameters were recorded before and 24 weeks after RTX therapy (2 infusions of 500 or 1,000 mg RTX intravenously, fortnightly): plasma total cholesterol (TC), high-density lip...

OBJECTIVES To evaluate the risk-benefit profile of anti-TNF therapies in PsA and to study the predictors of treatment response and disease remission [disease activity score (DAS)-28 < 2.6]. METHODS The study included PsA patients (n = 596) registered with the British Society for Rheumatology Biologics Register (BSRBR). Response was assessed using the European League against Rheumatism (EULAR)...

OBJECTIVES To determine the level of depression in Rheumatoid Arthritis and its relationship with severity of Rheumatoid Arthritis. METHODS This cross sectional analytical study was conducted from March 2014 to May 2014. Total 102 cases of Rheumatoid Arthritis (RA) diagnosed as per ACR (American College of Rheumatology) 1987 criteria were enrolled from Rheumatology Department, Fatima Memorial...

BACKGROUND The aim of this study was to evaluate sleep quality and the related variables in patients with rheumatoid arthritis (RA). METHODS Ninety-four patients diagnosed with RA and fifty two healthy controls were enrolled in the study. Disease activity was assessed through the Disease Activity Score (DAS) 28 scale. All patients were assessed using the Rheumatoid Arthritis Quality of Life a...

OBJECTIVE To examine the relationships between physical, psychological, and social factors and health-related quality of life (HRQOL) and disability in rheumatoid arthritis (RA). METHODS A sample of 106 patients with rheumatoid arthritis (RA) completed measures of self-reported disease activity and psychosocial functioning, including coping, personal mastery, social network, perceived stress,...

JUSTIFICATIVA E OBJETIVOS: A avaliação de gravidade e do prognóstico de pacientes obstétricas através de escores é ainda tema controverso, sendo escassa a informação sobre mulheres com pré-eclâmpsia. Esta é uma das maiores causas de morbidade materna grave e de mortalidade materna, além de ser também uma das principais causas de internação obstétrica em Uti. os objetivos deste estudo foram aval...

OBJECTIVE To investigate the accuracy of composite scores in classifying RA patients who are in remission using the absence of inflammatory activity detected by ultrasound (US) as a gold standard. METHODS Ninety-seven RA patients who were classified by their rheumatologists as being in remission were studied. Disease activity was assessed by the DAS-28 and simplified disease activity index (S...

As a current member of ACEN, I am pleased to have an opportunity in this column to profile briefly an upcoming CHSRF-funded study of Canadian nursing leadership. The study is officially entitled “A Profile of the Structure and Impact of Nursing Management in Canadian Hospitals,” and was approved for funding by the Canadian Health Services Research Foundation (Project Identifier: RC10964-06) in ...