Ferrite of austeno-ferritic stainless steels maintained for a long time at temperatures in the range of 270 °C to 400 °C is embrittled like the known 475 °C embrittlement of ferritic stainless steels. Deformation and damage micromechanisms of a material must be known in order to apply the “local approach to fracture” (LAF) methodology. In this work we test a previous model of damage nucleation ...

Biomarkers of acute kidney injury (AKI) may be classified in 2 groups: (1) those representing changes in renal function (e.g., serum creatinine or cystatin C and urine flow rate) and (2) those reflecting kidney damage (e.g., kidney injury molecule-1 (KIM-1), neutrophil gelatinase-associated lipocalin (NGAL), interleukin-18, etc.). According to these 2 fundamental criteria, 4 subgroups have been...

Owing to high specific strength and designability, unidirectional carbon fiber reinforced polymer (UD-CFRP) has been utilized in numerous fields to replace conventional metal materials. Post machining processes are always required for UD-CFRP to achieve dimensional tolerance and assembly specifications. Due to inhomogeneity and anisotropy, UD-CFRP differs greatly from metal materials in machini...

In psoriatic arthritis, permanent joint damage characterizes disease progression and represents a major debilitating aspect of the disease. Understanding the process of joint damage will assist in the treatment and disease management of patients. Multistate models provide a means to examine patterns of disease, such as symmetric joint damage. Additionally, the link between damage and the dynami...

A continuum damage mechanics (CDM) meso-model was derived for both intraply and interply progressive failure behaviors of a 2D woven-fabric composite laminate under a transversely low velocity impact. An in-plane anisotropic damage constitutive model of a 2D woven composite ply was derived based on CDM within a thermodynamic framework, an elastic constitutive model with damage for the fibre dir...

The goal of tort law and medical malpractice lawsuits is to restore the situation to its previous state. Namely, the compensation awarded to the victim aspires to return him to the situation before the damage was caused. However, this is not simple, since it is very difficult to measure mental damage or suffering experienced by the victim and to quantify it as financial payment. In tort lawsuit...

Immunoglobulin light-chain (AL) amyloidosis is caused by a usually small plasma cell clone synthesizing light chains undergoing conformational changes that lead to their aggregationanddeposition in tissues. This process leads toprogressivemultiple organdysfunction anddeath if left untreated.Advanced, irreversibleorgandamageatpresentation is the main limitation to improve theoutcomeofpatientswit...

Systemic sclerosis is a complex disease characterized by autoimmunity, vasculopathy and tissue fibrosis. Although most patients present with some degree of skin sclerosis, which is a distinguishing hallmark, the clinical presentation vary greatly complicating the diagnosis. In this regard, new classification criteria were jointly published in 2013 by American College of Rheumatology (ACR) and E...